Pharmaceutical lntermediates
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- Chemical Name: Epichlorohydrin
- CAS No.: 67843-74-7
- Molecular Fomula: ： C3H5ClO
- Molecular weight： 92.52
- Appearance: white powder
- Sample：Available
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Description of CHLOROMETHYLOXIRANE
S-enantiomer of Epichlorohydrin, an important industrial chemical, is a bifunctional alkylating agent with the potential to form DNA cross-links. It is used as a solvent for natural and synthetic resins, gums, cellulose esters and ethers, paints, varnishes, nail enamels and lacquers, cement for Celluloid. Also, it is used as stabilizer.
Basic Info of CHLOROMETHYLOXIRANE
Basic Info
Numbering system
Properties
Safety Info
Basic Info
| Chemical Name | (S)-epichlorohydrin |
| Synonyms | (2S)-2-(chloromethyl)oxirane;(S)-(+)-Epichlorohydrin; |
| CAS No. | 67843-74-7 |
| Molecular Formula | C3H5ClO |
| Molecular Weight | 92.52420 |
| PSA | 12.53000 |
| LogP | 0.62400 |
Numbering system
| MDL number | MFCD00077760 |
Properties
| Appearance & Physical State | Transparent liquid |
| Density | 1.183 |
| Boiling Point | 114ºC |
| Melting Point | -57ºC(lit.) |
| Flash Point | 33ºC |
| Refractive Index | 1.4365-1.4385 |
| Water Solubility | insoluble |
| Storage Condition | 2-8ºC |
| Vapor Density | 3.2 (vs air) |
| Vapor Pressure | 13.8 mm Hg ( 21.1 °C) |
Safety Info
| RTECS | TX4900000 |
| Hazard Class | 6.1 |
| Safety Statements | S45-S53 |
| HS Code | 2910900090 |
| Packing Group | II |
| WGK Germany | 3 |
| RIDADR | UN 2023 |
| Risk Statements | R10; R23/24/25; R34; R43; R45 |
| Hazard Codes | T |
What is Epichlorohydrin？
With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives. One such product is Epichlorohydrin which has developed particularly rapidly in recent years. Do you know about Epichlorohydrin ?
The official answer：Melting point -57°C(lit.) specific rotation 34º(589nm,c=1,MeOH) boiling point 92-93°C360mmHg(lit.) density 1.183g/mLat25°C(lit.) vapor density 3.2(vsair) vapor pressure 13.8mmHg(21.1 °C)Refractive indexn20/D1.438(lit.)Flash point93°F Storage conditionsInertatmosphere,2-8°C
What’s the application of Epichlorohydrin?
Dextro-epichlorohydrin, a variety of chiral pharmaceutical intermediates. Uses as potential metabolic regulators for the synthesis of fatty acid oxidation inhibitors; for the total synthesis of Macquarimicins and the total synthesis of the macrolide RK-397; chiral structural units for the enantioselective synthesis of hydroxyisoxazolidines and (+)-cis-sylvatic (a promising antitumor agent) Uses for chiral intermediates and chiral drugs Synthesis
Conclusion
Sincere to the customer and in good faith of quality is our forever followed motto. It’s the basement to be a human and do business. We take all responsibility for our products and service sincerely. We are a company integrating R&D, production, and sales. The design, research, and development of pharmaceutical intermediates including more than 330 kinds of pharmaceutical intermediates such as Anti-infectives, Cardiovascular and Cerebrovascular Systems, Digestive System, Santi-tumor, Nervous System, Geriatric Drugs, and Gynecological Drugs. At the same time, we have more than 4,000 factories in strategic cooperation with nearly 50,000 chemical products, so we can provide you with a one-stop purchasing service, which greatly saves customers’ procurement costs and time.
Keywords of Epichlorohydrin
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