β-Estradiol, Promotion Season Now in Store and Free Sample for Testing with Factory Price
- Chemical Name: β-Estradiol
- CAS No.: 50-28-2
- Molecular Fomula: : C18H24O2
- Molecular weight: 272.39
- Appearance: Milky white odorless crystalline powder
- Sample:Available
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Description of Dihydrofolliculin
Estradiol is the major estrogen secreted by the premenopausal ovary.
Basic Info of Ganciclovir sodium
Basic Info
Numbering system
Properties
Safety Info
Basic Info
Chemical Name | 17β-estradiol |
Synonyms | 17-Beta-Estradiol;17Beta-Estradiol;Estra-1,3,5(10)-triene-3,17-diol(17b)-;Estra-1,3,5(10)-triene-3,17-diol (17β)-; |
CAS No. | 50-28-2 |
Molecular Formula | C18H24O2 |
Molecular Weight | 272.38200 |
PSA | 40.46000 |
LogP | 3.60920 |
Numbering system
UNII | 4TI98Z838E |
Properties
Appearance & Physical State | white to off-white crystalline powder |
Density | 1.17g/cm3 |
Boiling Point | 445.9ºC at 760mmHg |
Melting Point | 173ºC |
Flash Point | 209.6ºC |
Refractive Index | 1.599 |
Stability | Stable. Incompatible with strong oxidizing agents. |
Storage Condition | 2-8ºC |
Safety Info
Hazard Class | 6.1 |
Safety Statements | S53-S45 |
Packing Group | III |
Risk Statements | R45 |
Hazard Codes | T |
Hazard Declaration | H351; H360Fd; H362 |
Signal Word | Danger |
Symbol | GHS08 |
Caution Statement | P201; P263; P281; P308 + P313 |
What is β-Estradiol?
- With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives. One such product is β-Estradiol which has developed particularly rapidly in recent years. Do you know about β-Estradiol ?
- The official answer:Estradiol is a steroidal estrogen, which is a white or milky white odorless crystalline powder; odorless. It is soluble in dioxane and acetone, slightly soluble in ethanol, and insoluble in water. There are two types, α, and β. The α type has strong physiological effects. It has been extracted from pregnant horse urine by Wintersteiner et al. (1935) and is also available from the urine of expectant mothers, human placenta, and pig ovaries. It is also present in the sperm ovaries or urine of male horses. Because of its strong sex hormone effect, it is believed that it or its esters are actually the most important sex hormones secreted by the ovaries.
What’s the application of β-Estradiol?
- Estrogenic drugs. Used for functional uterine bleeding, primary amenorrhea, menopausal syndrome, prostate cancer. Can promote and regulate the normal development of female sexual organs and paraphilias. It can promote the development and proliferation of breast ducts, but at higher doses, it can inhibit the release of prolactin from the anterior pituitary gland and reduce milk secretion. It can also be used to return milk. However, there may be nausea, vomiting, and bleeding due to excessive endometrial hyperplasia. Use with caution in cases of hepatic and renal insufficiency. Contraindicated in breast, vulva, and vaginal mucosa, as long as estrogen is secreted by the premenstrual ovaries. It relies on the regulation of gene transcription and protein synthesis during puberty to direct the development of female phenotypes and embryos, and also induces the production of gonadotropins and induces ovulation, intermediates of estradiol valerate and estradiol benzoate.
Conclusion
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