Chemical Name: N-2-Acetylguanine
CAS No: 19962-37-9
Molecular Fomula: C7H7N5O2
Molecular weight: 193.16
Appearance: White to beige Powder
Sample: Available
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Bretazenil (Ro16-6028) is an imidazopyrrolobenzodiazepine anxiolytic drug that is derived from the benzodiazepine family and was invented in 1988.
It is most closely related in structure to the benzodiazepine antagonist flumazenil, although its effects are somewhat different. It is classed as a high-potency benzodiazepine due to its high-affinity binding to benzodiazepine binding sites where it acts as a partial agonist. Its profile as a partial agonist and preclinical trial data suggests that it may have a reduced adverse effect profile. In particular, bretazenil has been proposed to cause a less strong development of tolerance and withdrawal syndrome.
Bretazenil differs from traditional 1,4-benzodiazepines by being a partial agonist and because it binds to α1, α2, α3, α4, α5, and α6 subunit-containing GABAA receptor benzodiazepine receptor complexes. 1,4-benzodiazepines bind only to α1, α2, α3 and α5 GABAA benzodiazepine receptor complexes.
Basic Info
Numbering system
Properties
Safety Info
Basic Info
Chemical Name | Lead oxide yellow |
CAS No. | 1317-36-8 |
Molecular Formula | OPb |
Molecular Weight | 223.19900 |
PSA | 17.07000 |
LogP | -0.49960 |
Numbering system
PubChem number | 24849302 |
EINECS number | 215-267-0 |
RTECS number | OG1750000 |
MDL number | MFCD00011164 |
Properties
Appearance & Physical State | Yellow powder, toxic. |
Density | 9.53 |
Boiling Point | 1470ºC |
Melting Point | 886ºC |
Refractive Index | 2.67 |
Stability | Stable. Reacts violently with hydrogen peroxide, strong oxidizing agents, aluminium, zirconium, halogens, sulphur trioxide, boron, silicon, sodium, zinc. |
Safety Info
Hazard Class | 6.1(b) |
Safety Statements | S45-S53-S60-S61 |
Packing Group | III |
RIDADR | UN 1479/2291 |
Risk Statements | R20/22; R33; R50/53; R61; R62 |
Hazard Codes | T; N |
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The official answer: Lead oxide is an inorganic substance with the chemical formula PbO, a yellow tetragonal crystalline powder. When heated to 300~450℃, it becomes lead tetraoxide, and then it becomes lead monoxide when it continues to heat up. Insoluble in water and ethanol, soluble in acetone, nitric acid, liquid alkali, ammonium chloride. Can react with glycerol to harden. Toxic.
Used in the manufacture of polyvinyl chloride plastic stabilizers. It is the raw material of other lead salts. In the paint industry, it is made into lead soap with oil and used as a drying agent in paint. Used in the manufacture of high refractive Chemicalbook optical glass, ceramic enamel, precision machine tool plane grinding agent, medical materials, rubber coloring agent. Also used in the manufacture of battery plates and petroleum refining, etc.
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