Trichloroacetic acid CAS# 76-03-9

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• Chemical Name:  Trichloroacetic acid
• CAS No.:     76-03-9
• Molecular Fomula: ： C2HCl3O2
• Molecular weight：163.39
• Appearance: Yellow lustrous flaky crystals
• Sample：Available

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Description of Aceto-Caustin

Trichloroacetic acid (TCA; TCAA; also known as trichloroethanoic acid) is an analogue of acetic acid in which the three hydrogen atoms of the methyl group have all been replaced by chlorine atoms. Salts and esters of trichloroacetic acid are called trichloroacetates.

Basic Info of Aceto-Caustin

Basic Info
Numbering system
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Safety Info
Basic Info

Numbering system

Properties

Safety Info

What is Trichloroacetic acid?

• With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives. One such product is Trichloroacetic acid   which has developed particularly rapidly in recent years. Do you know about Trichloroacetic acid?
• The official answer：Colorless crystals, with special odor, easily deliquescent. Soluble in ethanol, ether, acetone, benzene, carbon tetrachloride, hexane, o-xylene, and water, TCA is a colorless or white rhombohedral crystal. Strongly deliquescent. Slightly peculiar irritating odor. Strongly corrosive. Relative molecular mass 163.40. Relative density 1.6298(61℃). Melting point 57～58℃. Boiling point 197.5℃, 141～142℃(3.333×103Pa). The heat of combustion is 3.0kJ. Refractive index 1.4603(61℃). Vapor pressure 0.133×103Pa(51℃). Soluble in water, the aqueous solution is acidic (0.1mol aqueous solution pH1.2), soluble in ethanol, ether, solubility at 25℃: water 1306, methanol 2143, ether 617; aqueous solution below 30% decomposes slowly into chloroform, hydrogen chloride, carbon dioxide, carbon monoxide, etc.; hydrolysis in a dilute alkali solution to chloroform and carbon dioxide; hydrolysis in a concentrated alkali solution to formic acid. Decompose with strong alkali to chloroform and carbonate. Its aqueous solution is strongly acidic, mainly used in organic synthesis (such as drugs), can be used as a decalcifying agent and fixing agent when using a microscope. This product is strongly corrosive. Trichloroacetic acid is classified as highly toxic and must be used with due care. Oral toxicity is 3300mg/kg for mice and oral LD503320mg/kg for rats, and it can strongly irritate the skin and tissues. When attached to the skin, it can cause burns.

What’s the application of Trichloroacetic acid?

• Used as a chemical reagent, protein precipitation, and chromatographic analysis reagent Use as adenosine triphosphate, cytochrome C, and placental ester polysaccharide extractant and protein precipitant, also used as pesticide herbicide and organic synthesis raw material Use trichloroacetic acid is an intermediate of insecticide chlorpyrifos, also a pharmaceutical intermediate. UsesThe product is a wart remover and astringent in medicine, sodium trichloroacetate is a selective herbicide, mainly used as an extractant of biochemicals, such as adenosine triphosphate, cytochrome C, and placental ester polysaccharide, and other efficient drugs, also used as a raw material of pesticides, protein precipitant and Chemicalbook fixative of microscope samples. It is used for the determination of fluoride, protein precipitant, reagent for bile pigment together with ferric chloride, and fixative for microscopic analysis. It is used as a wart remover and astringent in medicine, and sodium trichloroacetate is a selective herbicide. It is mainly used as an extractant for biochemicals, such as adenosine triphosphate, cytochrome C and placental ester polysaccharide, and other highly effective drugs, and as a raw material for pesticides. Traditionally used for the precipitation of proteins. Used to determine protein concentration by quantitative precipitation. degree. Used as a decalcifying agent and as a fixative for microscopic samples. TCA is decomposed into chloroform and carbonate base by co-heating with an alkaline solution.

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