Caspofungin acetate CAS# 179463-17-3

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• Chemical Name:  Caspofungin acetate
• CAS No.:     179463-17-3
• Molecular Fomula: ：C54H92N10O17
• Molecular weight：1153.38
• Appearance: white powder
• Sample：Available

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Description of Cancidas

• Caspofungin (INN) (brand name Cancidas worldwide) is a lipopeptide antifungal drug from Merck & Co., Inc. discovered by James Balkovec, Regina Black and Frances A. Bouffard. It is a member of a new class of antifungals termed the echinocandins. It works by inhibiting the enzyme (1→3)-β-D-glucan synthase and thereby disturbing the integrity of the fungal cell wall. Caspofungin was the first inhibitor of fungal (1→3)-β-D-glucan synthesis to be approved by the United States Food and Drug Administration. Caspofungin is administered intravenously.

Basic Info of Cancidas

Basic Info
Numbering system
Properties
Safety Info
Basic Info

Numbering system

Properties

Safety Info

What is Caspofungin acetate?

• With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives. One such product is Caspofungin acetate   which has developed particularly rapidly in recent years. Do you know about Caspofungin acetate?
• The official answer：Caspofungin is a semi-synthetic lipopeptide (echinocandin) compound synthesized from the fermentation product of Glare Lozoyensis.
• Caspofungin inhibits the synthesis of β(1,3)-D-glucan, an essential component of the cell wall of many filamentous fungi and yeasts, and thus exerts antifungal effects.

What’s the application of Caspofungin acetate?

• Caspofungin acetate for injection is indicated in adult patients and pediatric patients (three months and older) for the empirical treatment of suspected fungal infections in neutropenic, febrile patients and for the treatment of invasive aspergillosis that is ineffective or intolerant to other treatments. Caspofungin has in vitro activity against Aspergillus spp. (including Aspergillus fumigatus, Aspergillus flavus, Aspergillus niger, Aspergillus oryzae, Aspergillus terreus, and Aspergillus albicans) and Candida spp. (including Candida albicans, Candida dublinensis, Candida smoothies, Candida gilimontica, Candida lactis, Candida krusei, Candida lysis, Candida Portuguese, Candida subsmoothus, Candida rugosa, and Candida tropicalis).

Conclusion

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