Triphosgene Typical Properties

Triphosgene Usage

1. The carbonylation reaction of phosgene and primary amine can prepare various isocyanates, but since phosgene is difficult to measure accurately, side reactions often occur.
2. Triphosgene is a solid and can be accurately measured, and the use of triphosgene instead of phosgene greatly improves its safety, so it can safely replace phosgene.
3. The reaction of triphosgene with amine compounds is a widely used field. The reaction has strong selectivity, and some functional groups do not require protection, and can directly generate compounds such as isocyanate and urea. Carbonylation reaction of triphosgene and various primary amines can synthesize various isocyanates. The reaction only needs to accurately control the ratio of triphosgene and amine, and the target product can be obtained without any by-products. For example, the reaction of triphosgene with 2,4-diaminotoluene can synthesize 2,4-dimethyldiisocyanate (TDI); the reaction of triphosgene with 4,4′-diaminodiphenylmethane can generate 4,4′-bis Phenylmethane diisocyanate (MDI); triphosgene and hexamethylene diamine can produce sodium hexamethylene diisocyanate (HDI).
4. In the carbonylation reaction of BTC, cyclization condensation reaction can also be carried out. In this type of reaction, triphosgene is widely used. It can be used to prepare N-carbonyl anhydride, as well as various important heterocyclic compounds and cyclic carbonate compounds. The former can be used to prepare active amino acid and polypeptide compounds, and the latter can be used to prepare various pharmaceutical and pesticide intermediates.

Triphosgene Packaging

25kgs per drum

Triphosgene Storage

Cool dry place.