Tofacitinib, Promotion Season Now in Store and Free Sample for Testing with Factory Price
- Chemical Name: Tofacitinib
- CAS No.:4767-03-7
- Molecular Fomula:C16H20N6O
- Molecular weight:312.38
- Appearance:Pale powder
- Sample: Available
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Description of Tofacitinib
CP-690550 is a pyrrolo[2,3-d]pyrimidine derivative, as Janus kinase inhibitor for treatment of rheumatoid arthritis.
Basic Info of Tofacitinib
Basic Info
Numbering system
Properties
Basic Info
Chemical Name | CS-344 |
Synonyms | (3R,4R)-4-methyl-3-(methyl-1H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-β-oxo-1-piperidinepropanenitrile;CS-344;Tasocitinib; |
CAS No. | 477600-75-2 |
Molecular Formula | C16H20N6O |
Molecular Weight | 312.37000 |
PSA | 88.91000 |
LogP | 1.48268 |
Numbering system
UNII | 87LA6FU830 |
Properties
Density | 1.296g/cm3 |
Boiling Point | 585.845ºC at 760 mmHg |
Flash Point | 308.108ºC |
Refractive Index | 1.646 |
What is Tofacitinib?
With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives. One such product is it which has developed particularly rapidly in recent years. Do you know about it?
The official answer:CS-344, a JAK inhibitor developed by Pfizer, effectively inhibits the activity of JAK1 and JAK3 and blocks the signaling of a variety of inflammatory cytokines.
What’s the application of Tofacitinib?
CS-344 is indicated for adult patients with moderately to severely active rheumatoid arthritis (RA) for whom methotrexate is not effective or not tolerated and may be used in combination with methotrexate or other non-biologic disease-modifying anti-rheumatic drugs (DMARD).
Conclusion
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