Side Train of Ertapenem CAS# 202467-69-4

Ertaipenem side chain, Promotion Season Now in Store and Free Sample for Testing with Factory Price

• Chemical Name:  Side Train of Ertapenem
• CAS No.:     202467-69-4
• Molecular Fomula: ：C20H19N3O7S
• Molecular weight：445.45
• Appearance: Colorless liquid
• Sample：Available

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Description of Ertaipenem side chain

3-[[[(2S,4S)-1-(4-Nitrobenzyloxycarbonyl)-4-mercaptopyrrolidin-2-yl]carbonyl]amino]benzoic Acid is an intermediate in the preparation of Ertapenem and intermediates.

Basic Info of Ertaipenem side chain

Basic Info
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Safety Info
Basic Info

Numbering system

Properties

Safety Info

What is Side Train of Ertapenem?

• With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives. One such product is Side Train of Ertapenem   which has developed particularly rapidly in recent years. Do you know about Side Train of Ertapenem  ?
• The official answer：Carbapenem antibiotics are new β-lactam antibiotics that are stable to β-lactamases. They are classified into 3 types according to the antibacterial spectrum. Type 1: Broad-spectrum carbapenems with limited antibacterial activity against non-fermentative gram-negative bacilli, such as ertapenem, for community-acquired infections. Type 2: Broad-spectrum with antibacterial activity against non-fermentative gram-negative bacilli, such as imipenem and meropenem, for hospital-acquired infections. Type 3: Clinically active against drug-resistant staphylococci, not yet available. Carbapenem antibiotics can be used effectively for moderate to severe infections caused by bacterial multi-drug resistance and are considered an important line of defense against infection in humans. With the increasing severity of bacterial resistance problems, there is a growing interest in carbapenem antibiotics. Among the marketed panel varieties, ertapenem is a very distinctive one with a long plasma half-life due to the benzoic acid structure in its structure, making it a novel broad-spectrum carbapenem antibiotic with novel structure, non-gastrointestinal delivery, long-acting, and stability to DHP-1. Ertapenem sodium (ertapenem), chemically named (1R,5S,6S,8R,2S*,4S*)-2-[2-[3-carboxy-phenylcarbamoyl]-pyrrolidinyl-4-thio]-6-(1-hydroxyethyl)-1-methylcarbapenem-3-carboxylic acid monosodium salt, was developed by Merck and launched in the United States and Europe in November 2001 and April 2002, respectively. It was marketed in the United States and Europe in November 2001 and April 2002 respectively, and then in the United Kingdom, Ireland, Israel, and the Philippines, and in China in 2005. It has good antibacterial activity and pharmacokinetic properties, with a long half-life, and satisfactory results can be obtained with one daily dose. It has been approved for the treatment of complicated abdominal infections, complicated skin tissue infections, complicated urinary tract infections, and gynecological infections in adults, and can be used in young children over 3 months of age, so it has great market potential.

What’s the application of Side Train of Ertapenem?

• It is indicated for the treatment of a wide range of bacterial infections in adults, including intra-abdominal infections, skin and skin tissue infections, urinary tract infections, obstetrical and gynecological infections, and pneumonia. The chemical name of Ertapenem side chain II is 3-[(2S,4S)-4-mercaptopyrrolidine-2-carbamido]benzoic acid hydrochloride. Ertapenem (MK-0826, L-749, trade name Invanztm) is a new broad-spectrum, long-acting 1β-methylcarbapenem antibiotic developed by Merck in the United States and marketed in the United States and Europe in November 2001 and April 2002, respectively. It has good antibacterial activity and pharmacokinetic properties and has significant effects on both Gram-positive and negative aerobic and anaerobic bacteria. Ertapenem side chain II is the deprotective side chain of Ertapenem.

Conclusion

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