Raloxifene, Promotion Season Now in Store and Free Sample for Testing with Factory Price
- Chemical Name: Raloxifene
- CAS No.: 84449-90-1
- Molecular Fomula: C28H27NO4S
- Molecular weight: 473.58300
- Appearance: Light-Yellow Solid
- Sample: Available
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Description of UNII-YX9162EO3I
Raloxifene (marketed as Evista by Eli Lilly and Company) is an oral selective estrogen receptor modulator (SERM) that has estrogenic actions on bone and anti-estrogenic actions on the uterus and breast. It is used in the prevention of osteoporosis in postmenopausal women and to reduce the risk of invasive breast cancer in postmenopausal women with osteoporosis and in postmenopausal women at high risk for invasive breast cancer.
Basic Info of Raloxifene
Basic Info
Numbering system
Properties
Safety Info
Basic Info
| Chemical Name | raloxifene |
|---|---|
| Synonyms | [2-(4-Hydroxyphenyl)-6-hydroxybenzo[b]thien-3-yl] [4-[2-(1-piperidinyl)ethoxy]phenyl]methanone;Raloxifeno;6-hydroxy-2-(4-hydroxyphenyl)-3-[4-(2-piperidino-ethoxy)benzoyl]benzo[b]thiophene;UNII-YX9162EO3I;Raloxifenum [Latin] |
| CAS No. | 84449-90-1 |
| Molecular Formula | C28H27NO4S |
| Molecular Weight | 473.58300 |
| PSA | 98.24000 |
| LogP | 6.01310 |
Numbering system
| MDL number | MFCD00866415 |
|---|
Properties
| Appearance & Physical State | Light-Yellow Solid |
|---|---|
| Density | 1.289 g/cm3 |
| Boiling Point | 728.2ºC at 760 mmHg |
| Melting Point | 250-253ºC |
| Flash Point | 394.2ºC |
| Storage Condition | Store in original container in a cool dark place. |
Safety Info
| WGK Germany | 3 |
|---|
What is UNII-YX9162EO3I?
With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives. One such product is UNII-YX9162EO3I which has developed particularly rapidly in recent years. Do you know about UNII-YX9162EO3I?
The official answer: UNII-YX9162EO3I is a white to yellowish-white crystal or crystalline powder with a melting point (ºC) of 250-253 °C. It is soluble in chloroform or dimethylformamide, more soluble in acetonitrile, acetone or ethyl acetate, less soluble in methanol, anhydrous ethanol or anhydrous ethyl ether, and insoluble in ethane, and almost insoluble in water. It is used for the treatment of post-menopausal osteoporosis in women.
What’s the application of UNII-YX9162EO3I?
Uses: For the prevention and treatment of osteoporosis in postmenopausal women, in estrogen-dependent patients. Drug Interactions1. Combined with warfarin may shorten prothrombin time.2. May alter prothrombin time in patients already receiving coumarin-based anticoagulants. Contraindications 1. contraindicated in women who may be pregnant. 2. Contraindicated in patients with current or previous venous thromboembolic disease, including deep vein thrombosis, pulmonary embolism and retinal vein thrombosis. 3. Contraindicated in patients with hypersensitivity to this product. 4. Contraindicated in patients with hepatic decompensation (including cholestasis), severe renal decompensation. 5. Contraindicated in patients with endometrial cancer and in patients with unexplained uterine bleeding. Adverse reactions may be seen as a mild decrease in platelet count.Chemicalbook Occasional nausea, vomiting, abdominal pain and dyspepsia, rash, increased blood pressure, headache, mild increase in aminotransferase. Chemical propertiesCrystalline from acetone, melting point 143-147°C. UV greatest absorption (ethanol): 290nm (ε34000). UNII-YX9162EO3IHydrochloride: C28H27NO4S?HCl.[8264000408]. Crystallized from methanol-water, melting point 258°C. UV largest absorption (ethanol): 286 nm (ε32800). UsesSelective estrogen receptor modulator, for postmenopausal osteoporosis. UsesSelective estrogen regulator, prevention of osteoporosis.
Conclusion
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