Carboxymethylchitosan, Promotion Season Now in Store and Free Sample for Testing with Factory Price
- Chemical Name: Carboxymethylchitosan
- CAS No.: 83512-85-0
- Molecular Fomula: C8H15NO6
- Molecular weight: 221.20800
- Appearance: White powdery solid
- Sample: Available
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Basic Info of Carboxymethylchitosan
Basic Info
Basic Info
| Chemical Name | Carboxymethyl chitosan |
|---|---|
| Synonyms | Carboxymethyl chitin |
| CAS No. | 83512-85-0 |
| Molecular Formula | C8H15NO6 |
| Molecular Weight | 221.20800 |
| PSA | 122.24000 |
| LogP | -1.41660 |
What is chitin?
- With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives.
- One such product is chitin which has developed particularly rapidly in recent years. Do you know about chitin?
- The official answer: chitin is an important water-soluble chitosan derivative with many medical properties, such as promoting wound healing, haemostasis, scar inhibition, analgesia and antibacterial effects, and also has a wide range of applications in chemicals, environmental protection and nutraceuticals. Also, carboxymethyl chitosan can be processed into nanoparticles, making it more suitable for drug delivery, bioimaging, biosensors and gene therapy. In recent years, carboxymethyl chitosan has also found many applications in green chemistry. Due to its unique biological properties,carboxymethyl chitosan has a wide range of applications in the biomedical and pharmaceutical fields. A solution of sodium hydroxide in isopropanol was added to the reaction flask at a concentration of 40% sodium hydroxide. Add chitosan with a deacetylation degree of 15% to 45% to the reaction flask, and the mass ratio of chitosan to sodium hydroxide after addition is 1:4.8. Add the pre-dissolved isopropanol solution of chloroacetic acid to the reaction flask and dropwise with stirring, and continue to stir the reaction for 3 h. The mass ratio of chitosan to chloroacetic acid is 5:1. After the reaction is completed, add concentrated hydrochloric acid to the post-reaction material and adjust the pH of the material to 6-7. The filter cake was washed 3 times with anhydrous ethanol and dried at 50°C to get the crude carboxymethyl chitosan.The purification method of purifying carboxymethyl chitosan, including the following steps: 1) dissolve 40Kg of carboxymethyl chitosan with the isoelectric point at pH 2.7, number average molecular weight of 40W, carboxymethyl substitution degree of 1.3 in 2 tons of water Chemicalbook, adjust the pH of the aqueous solution of carboxymethyl chitosan to 2.7, so that carboxymethyl chitosan forms a white flocculent precipitate, centrifuge and dehydrate to get 2) washing the concentrated carboxymethyl chitosan obtained in 1) with filtered water at pH 2.7 to remove the salt contained in the concentrated carboxymethyl chitosan to get desalted carboxymethyl chitosan; 3) washing said desalted carboxymethyl chitosan with ethanol at a concentration of 95% to an alcoholic strength of 95° in the supernatant, removing the supernatant and centrifuging and drying to get 99.3% purity of The carboxymethyl chitosan was 99.3%. The above purification process was completed with a total of 430 kg of 95% ethanol, compared to the prior art where 2 tons of 95% ethanol were required to purify 40 kg of the same carboxymethyl chitosan, saving the amount of ethanol, reducing production costs, reducing the emission of waste alcohol and avoiding damage to the environment.
What’s the application of chitin?
- Used as a high grade cosmetic additive, heavy metal chelator, drug retarder, plant growth agent, etc. chitin (CMC) is a carboxymethylated derivative of chitosan, which is polar and soluble in water and has been used in pharmaceuticals and biomedical materials development.
- Chemicalbook is particularly important for the accurate quantification of carboxymethyl chitosan as the amount of carboxymethyl chitosan in a drug affects its antibacterial and anti-infective clinical effects.
Conclusion
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