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- Chemical Name: Phenylbutazone
- CAS No.: 50-33-9
- Molecular Fomula: :C19H20N2O2
- Molecular weight:308.37
- Appearance: whiite powder
- Sample:Available
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Description of bizolin
Phenylbutazone, often referred to as “bute”, is a nonsteroidal anti-inflammatory drug (NSAID) for the short-term treatment of pain and fever in animals.
In the United States and United Kingdom, it is no longer approved for human use, as it can cause severe adverse effects such as suppression of white blood cell production and aplastic anemia. This drug was implicated in the 2013 meat adulteration scandal. Positive phenylbutazone tests in horse meat were uncommon in the UK, however.
Basic Info of bizolin
Basic Info
Numbering system
Properties
Safety Info
Basic Info
Chemical Name | phenylbutazone |
Synonyms | Azdid;A 7514;1,2-diphenyl-4-butyl-3,5-dioxopyrazolidine;Buzon;Phenylbutazone;Expand |
CAS No. | 50-33-9 |
Molecular Formula | C19H20N2O2 |
Molecular Weight | 308.37400 |
PSA | 40.62000 |
LogP | 3.91780 |
Numbering system
UNII | GN5P7K3T8S |
Properties
Appearance & Physical State | off-white powder |
Density | 1.173g/cm3 |
Boiling Point | 424.9ºC at 760mmHg |
Melting Point | 104-107ºC |
Flash Point | 174.3ºC |
Refractive Index | 1.606 |
Stability | Stable. Incompatible with strong oxidizing agents, strong acids, strong bases. |
Storage Condition | -20ºC Freezer |
Safety Info
RTECS | UQ8225000 |
Hazard Class | 6.1(b) |
Safety Statements | S53-S22-S26-S36/37/39-S45 |
HS Code | 2933199090 |
Packing Group | III |
RIDADR | UN 3249 |
Risk Statements | R45; R20/21/22; R36/37/38; R42/43 |
Hazard Codes | T |
Signal Word | Danger |
Symbol | GHS06 |
Hazard Declaration | H301; H312; H315; H319; H332; H335 |
Caution Statement | P261; P280; P301 + P310; P305 + P351 + P338 |
What is Phenylbutazone?
- With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives. One such product is Phenylbutazone which has developed particularly rapidly in recent years. Do you know about Phenylbutazone?
- The official answer:It is obtained by the cyclization of hydrogenated azobenzene and diethyl butylmalonate. Hydroazobenzene, diethyl butylmalonate, sodium methanol, and sodium sulfite are heated together and refluxed vigorously for 1.5h to produce the sodium salt of pautaxone, and then acidified with acetic acid to obtain pautaxone white or off-white crystalline powder. Melting point 105.5-106.5℃. Freely soluble in acetone, chloroform, or benzene, soluble in ethanol or ether, almost insoluble in water, soluble in sodium hydroxide solution. Odorless, slightly bitter taste.
What’s the application of Phenylbutazone?
- It has antipyretic and analgesic, anti-inflammatory, and anti-rheumatic effects, mainly used for the treatment of rheumatic and rheumatoid arthritis and gout, for the treatment of rheumatoid arthritis and gout, and other conditions, non-steroidal anti-inflammatory drugs. Antipyretic and analgesic, used for rheumatic and rheumatoid arthritis and gout, etc. POTAXONE is a drug that acts on the central nervous system and belongs to pyrazolone derivatives, with weak antipyretic and strong anti-inflammatory effects, good effect on inflammatory pain, and can promote the excretion of uric acid. The antipyretic and analgesic effect of Protaxone is inferior to that of acetylsalicylic acid, and it is more toxic, so it is generally not used as an antipyretic and analgesic drug, but its anti-inflammatory effect is stronger and can be used for the treatment of rheumatic and rheumatoid arthritis, acute gouty arthritis and ankylosing spondylitis. In addition, it can reduce the reabsorption of urate from the renal tubules and has a mild urinary excretory effect, and can also be used in patients with acute gout. It is often given continuously or in combination with other drugs. It can also be used to treat fever caused by acute schistosomiasis, filarial acute lymphangitis, tuberculosis, malignant tumors, etc.
Conclusion
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