Lactic acid CAS# 50-21-5

2-Hydroxy-2-methylacetic acid, Promotion Season Now in Store and Free Sample for Testing with Factory Price

• Chemical Name:2-Hydroxy-2-methylacetic acid
• CAS No.:     50-21-5
• Molecular Fomula: ：C3H6O3
• Molecular weight：90.08
• Appearance: Colorless to yellow syrup
• Sample：Available

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Description of 2-Hydroxy-2-methylacetic acid

Lactic acid is an organic compound with the formula CH3CH(OH)CO2H. In its solid state, it is white and water-soluble. In its liquid state, it is clear. It is produced both naturally and synthetically. With a hydroxyl group adjacent to the carboxyl group, lactic acid is classified as an alpha-hydroxy acid (AHA). In the form of its conjugate base called lactate, it plays a role in several biochemical processes.
In solution, it can ionize a proton from the carboxyl group, producing the lactate ion CH 3CH(OH)CO− 2. Compared to acetic acid, its pKa is 1 unit less, meaning lactic acid deprotonates ten times more easily than acetic acid does. This higher acidity is the consequence of the intramolecular hydrogen bonding between the α-hydroxyl and the carboxylate group.
Lactic acid is chiral, consisting of two optical isomers. One is known as L-(+)-lactic acid or (S)-lactic acid and the other, its mirror image, is D-(−)-lactic acid or (R)-lactic acid. A mixture of the two in equal amounts is called DL-lactic acid, or racemic lactic acid.
Lactic acid is hygroscopic. DL-lactic acid is miscible with water and with ethanol above its melting point which is around 17 or 18°C. D-lactic acid and L-lactic acid have a higher melting point.
In animals, L-lactate is constantly produced from pyruvate via the enzyme lactate dehydrogenase (LDH) in a process of fermentation during normal metabolism and exercise. It does not increase in concentration until the rate of lactate production exceeds the rate of lactate removal, which is governed by a number of factors, including monocarboxylate transporters, concentration and isoform of LDH, and oxidative capacity of tissues. The concentration of blood lactate is usually 1–2 mmol/L at rest, but can rise to over 20mmol/L during intense exertion and as high as 25mmol/L afterward.
In industry, lactic acid fermentation is performed by lactic acid bacteria, which convert simple carbohydrates such as glucose, sucrose, or galactose to lactic acid. These bacteria can also grow in the mouth; the acid they produce is responsible for the tooth decay known as caries.
In medicine, lactate is one of the main components of lactated Ringer’s solution and Hartmann’s solution. These intravenous fluids consist of sodium and potassium cations along with lactate and chloride anions in solution with distilled water, generally in concentrations isotonic with human blood. It is most commonly used for fluid resuscitation after blood loss due to trauma, surgery, or burns.

Basic Info of 2-Hydroxy-2-methylacetic acid

Basic Info
Numbering system
Properties
Safety Info
Basic Info

Numbering system

Properties

Safety Info

What is Lactic acid ?

• With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives. One such product is 2-Hydroxy-2-methylacetic acid   which has developed particularly rapidly in recent years. Do you know about 2-Hydroxy-2-methylacetic acid  ?
• The official answer：2-Hydroxy-2-methylacetic acid is an important organic acid, the second organic acid after citric acid in terms of production and consumption, and some information shows that the consumption of 2-Hydroxy-2-methylacetic acid accounts for about 15% of the total consumption of organic acids. In recent years, due to the expansion of L-2-Hydroxy-2-methylacetic acid in biodegradable plastics, its demand will have a large rate of growth, and some predict that it may catch up with or exceed citric acid in a few years. 2-Hydroxy-2-methylacetic acid is widely found in nature and is found in living organisms. 2-Hydroxy-2-methylacetic acid, also known as 2-hydroxy propionic acid and alpha-hydroxy propionic acid, has an asymmetric carbon atom in its molecular structure, forming two spin isomers d-body, l-body, and racemic dl-body, with a total of three optical isomers. 1780 Scheele obtained this product in sour milk, hence the name 2-Hydroxy-2-methylacetic acid. The dextro- and racemic bodies are present in human and animal tissues, while the Levo-body is a normal metabolite in mammals. It is also found naturally in poppy, apple, tomato juice, and other fruits. Commercially available products, whether made by fermentation or synthesis, are racemic. Due to the presence of hydroxyl and carboxyl groups in the molecule, this product has the effect of both functional groups, generating carboxylic acid esters with an acid anhydride, 2-Hydroxy-2-methylacetic acid esters with alcohols, and salts with sodium, calcium, and ferrous ions; since this product has both hydroxyl and carboxyl groups, it can undergo self-esterification to generate linear polyesters, and even cyclic compounds, i.e., to generate cyclic dimeric propyleneglycerides [2]. Oxidized under slow conditions, this product can produce pyruvic acid, and when heated above 250°C it breaks the chain and decomposes to produce acetaldehyde, giving off carbon dioxide and water. Reaction with ammonia or amine can produce 2-Hydroxy-2-methylacetic acid amide. In addition to self-esterification, the hydroxyl and carboxyl groups of this product can also participate in the reaction at the same time, such as the reaction with aldehyde or ketone, which can produce cyclic acetal. In medicine, it is used as the sodium salt of 2-Hydroxy-2-methylacetic acid to prevent acidosis, iron lactate and calcium lactate are raw materials for the pharmaceutical industry, ethyl lactate is a spice, butyl lactate is a good auxiliary for lacquer and important raw material for plasticizer and improver in the plastic industry; it is used as rust remover in electroplating industry.

What’s the application of Lactic acid ?

• Mainly used in spices, food, beverage industry, but also pharmaceutical, chemical, leather, printing and dyeing industries, raw materials used as experimental reagents, edible spices, preservatives, plasticizers, and adhesives, also used in the pharmaceutical industry for antibacterial synergistic drug uses 2-Hydroxy-2-methylacetic acid to make an important acidifier, with a special astringent acid taste. Can be used in all kinds of food, according to the production needs of the appropriate amount of use. It also has a strong bactericidal effect and can prevent the growth of miscellaneous bacteria. 2-Hydroxy-2-methylacetic acid is an important acidifier, with a specific astringent acid taste. It can be used in all kinds of foodstuffs and used inappropriate amounts according to the production needs. It also has a strong bactericidal effect and can prevent the growth of miscellaneous bacteria. 2-Hydroxy-2-methylacetic acid is a very versatile organic acid and can be used in brewing, medicine, leather, cigarettes, chemicals, food, printing, dyeing, etc. The distribution of 2-Hydroxy-2-methylacetic acid in Japan is approximately 20% for brewing, 50% for food, 10% for 2-Hydroxy-2-methylacetic acid derivatives, and 20% for leather and other industries. The distribution of uses in Japan is also similar. 1. 80% of 2-Hydroxy-2-methylacetic acid is used in the brewing industry. The addition of 2-Hydroxy-2-methylacetic acid prevents the multiplication of miscellaneous bacteria, promotes the development of yeast, prevents the cloudiness of wine and enhances the flavor of wine, and also improves the yield of wine. 2. Food industry The food industry generally uses 2-Hydroxy-2-methylacetic acid with a content of 50%. It is mainly used in 2-Hydroxy-2-methylacetic acid drinks, refreshing beverages, pastries, savory dishes, and acidulants. 2-Hydroxy-2-methylacetic acid can make the food slightly acidic without masking the natural flavor and fragrance of fruits and steamed vegetables. Therefore, it is widely used in tomatoes, oil olives, pickled cucumbers, pickled cabbage, and other canned foods, and sour milk drinks made from 2-Hydroxy-2-methylacetic acid bacteria are also very popular. 3. pharmaceutical industry 2-Hydroxy-2-methylacetic acid can be directly formulated into drugs or made into lactates for use. It can be used internally for intestinal disinfection. It can also dissolve proteins and keratin and is particularly sensitive to the corrosive effect of diseased tissue, so it can be used to treat laryngeal tuberculosis, diphtheria, lupus, and other diseases. In addition, it is also used in fencing sterilization: couching agent, coating agent, bladder injection, vaginal wash. 2-Hydroxy-2-methylacetic acid is used to combine with insoluble drugs to increase the absorption of drugs and prevent side effects. 2-Hydroxy-2-methylacetic acid is also a raw material for making erythromycin sugar coating, so it is widely used in the pharmaceutical industry.4. The leather industry generally leather with a 2-Hydroxy-2-methylacetic acid content of 40% can be. It does not require high quality of 2-Hydroxy-2-methylacetic acid, dark color and with odor can be used, the tanning industry mainly uses it to remove the lime in tanned leather, also called de-ash, with 2-Hydroxy-2-methylacetic acid de-ash leather quality than another acid de-ash quality is good, also to senior leather must be treated with 2-Hydroxy-2-methylacetic acid. In cigarette production, 2-Hydroxy-2-methylacetic acid can be used to remove impurities in tobacco and remove the bitter and spicy taste, therefore, the grade of low-grade tobacco can be improved by 2-Hydroxy-2-methylacetic acid treatment. 2-Hydroxy-2-methylacetic acid is used as a pH control agent in celluloid paint production; in the wool industry for pre-chromium mordanting of dyes to reduce the chromate content of wool and prevent oxidation of fibers; in the post-treatment of silk and rayon, it is used as a pH regulator for color enhancement treatment to increase the color of yarn. Pure 2-Hydroxy-2-methylacetic acid is odorless, and the commodity has a slightly cool milk-like aroma, and when the concentration is appropriate, it has a pleasantly sour taste. When 2-Hydroxy-2-methylacetic acid is used as raw material, it is mostly used as a component of butter, cool milk, butter hard candy, milk, cheese, and other dairy products flavors. The main derivatives of 2-Hydroxy-2-methylacetic acid: calcium stearoyl lactate is used as a food additive, adding 0.3%-0.5% of calcium stearoyl lactate in flour can make the bread puffy, increase the volume by 30%-40% and delay the aging. When sodium lactate is used as a flavoring agent, it is used as a casein plastic whitening agent, antifreeze, moisturizing agent, and drug production. The calcium lactate is used as a nutritional fortification agent. Ferrous Lactate is used for food fortification and pharmaceutical treatment of iron deficiency anemia, etc. 2-Hydroxy-2-methylacetic acid esters, including methyl ester, ethyl ester, butyl ester, etc. are used as solvents, flavor enhancers, etc. 2-Hydroxy-2-methylacetic acid and its derivatives such as sodium and calcium salts are non-toxic and are safe food additives. Stearoyl lactate is used in emulsifiers and baked goods; sodium lactate is used for intravenous injection; synthetic 2-Hydroxy-2-methylacetic acid is used in place of natural fermented 2-Hydroxy-2-methylacetic acid in cheese and other dairy products to acidify and curdle milk or cream. These three uses have multiplied the production of 2-Hydroxy-2-methylacetic acid in the United States. The potential market for 2-Hydroxy-2-methylacetic acid is large as the food industry grows. Used for complex titration analysis of calcium, magnesium, and aluminum; for measuring carbon dioxide binding in plasma; for determining copper and zinc uses acids and flavors for food, preservatives, preparation of lactates, plasticizers, complex titration analysis, magnesium, and aluminum, for measuring carbon dioxide binding in plasma, for determining copper and zinc.

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