AMG 145, Promotion Season Now in Store and Free Sample for Testing with Factory Price
- Chemical Name: Evolocumab
- CAS No.: 1256937-27-5
- Molecular Fomula: ：
- Molecular weight：
- Appearance: white powder
- Sample：Available
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Basic Info of AMG 145
Basic Info
Numbering system
Basic Info
| Chemical Name | Evolocumab |
| Synonyms | |
| CAS No. | 1256937-27-5 |
| Molecular Formula | |
| Molecular Weight | 0.00000 |
| PSA | 0.00000 |
| LogP | 0.00000 |
Numbering system
| UNII | LKC0U3A8NJ |
What is Evolocumab?
- With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives. One such product is Evolocumab which has developed particularly rapidly in recent years. Do you know about Evolocumab ?
- The official answer：Eloizumab (Evolocumab) is a human monoclonal immunoglobulin G2 (IgG2) that effectively reduces LDL-C levels in patients with dyslipidemia. Evolocumab was approved for marketing by the European Medicines Agency (EMA) on July 17, 2015, by the U.S. Food and Drug Administration (FDA) on August 27, 2015, by the Pharmaceutical and Medical Devices Agency (PMDA) in Japan on January 22, 2016, and by the State Drug Administration (NMPA) in China on July 31, 2018. ) approval for marketing in China under the trade name Rebaan, with indications for the treatment of adults or adolescents over 12 years of age with pure subtype familial hypercholesterolemia and for the treatment of adults with atherosclerotic cardiovascular disease to reduce the risk of myocardial infarction, stroke, and coronary artery revascularization.
What’s the application of Evolocumab?
- Eloyumab, a human monoclonal IgG2 antibody, is a PCSK9 inhibitor that selectively binds to PCSK9 and prevents PCSK9 in the blood from binding to LDLR on the surface of hepatocytes, thereby preventing PCSK9-mediated LDLR degradation and allowing LDLR to circulate smoothly back to the surface of hepatocytes. By inhibiting the binding of PCSK9 to LDLR, denosumab increases the amount of LDLR, thereby removing LDL-C from the blood.
Conclusion
Sincere to the customer and in good faith of quality is our forever followed motto. It’s the basement to be a human and do business. We take all responsibility for our products and service sincerely. We are a company integrating R&D, production, and sales. The design, research, and development of pharmaceutical intermediates including more than 330 kinds of pharmaceutical intermediates such as Anti-infectives, Cardiovascular and Cerebrovascular Systems, Digestive System, Santi-tumor, Nervous System, Geriatric Drugs, and Gynecological Drugs. At the same time, we have more than 4,000 factories in strategic cooperation with nearly 50,000 chemical products, so we can provide you with a one-stop purchasing service, which greatly saves customers’ procurement costs and time.
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