Ethynyl estradiol CAS# 57-63-6

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• Chemical Name:  Ethynyl estradiol
• CAS No.:     57-63-6
• Molecular Fomula: ：C20H24O2
• Molecular weight：296.41
• Appearance: White crystalline powder
• Sample：Available

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Description of 17BETA-DIOL

Ethinyl estradiol, also sometimes written as 17α-ethinyl estradiol, ethinylestradiol, ethynyl estradiol, or ethinyl œstradiol, is a derivative of 17β-estradiol (E2), the major endogenous estrogen in humans. EE2 is an orally bioactive estrogen used in many formulations of combined oral contraceptive pills and is one of the most commonly used medications for this purpose.
Transdermal ethinyl estradiol carries a greater risk of clot formation and venous thromboembolism than naturally occurring 17β-estradiol, which some have theorized to be related to different amounts of hepatic metabolism after absorption. The same contraindications and precautions apply for EE2 as with other estrogen medications.
Estinyl was a preparation of EE2 alone that was used for the management of menopausal symptoms and female hypogonadism.
EE2 is released into the environment as a xenoestrogen from the urine and feces of people who take it as a medication.
The major concern with unopposed estrogen (without progestogen) is of endometrial cancer. As such, the medication is generally prescribed with progesterone in the setting of birth control.

Basic Info of 17BETA-DIOL

Basic Info
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Basic Info

Numbering system

Properties

Safety Info

What is Ethynyl estradiol ?

• With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives. One such product is Ethynyl estradiol   which has developed particularly rapidly in recent years. Do you know about Ethynyl estradiol?
• The official answer：White to milky white crystalline powder. Melting point 145-146°C (hemihydrate). 182-184°C (anhydrous). Soluble in ethanol, propanol, ether, chloroform, dioxane, vegetable oil, and sodium hydroxide solution, almost insoluble in water. Odorless. Melting point182-183°C(lit.)Boiling point378°C(rough estimate)Density1.0944(rough estimate)Refractive index-30°(C=0.4,Pyridine)Flash point9°CStorage conditionroomtemp Solubilityethanol:50mg/mL,clear, slightly yellow.

What’s the application of Ethynyl estradiol ?

• This product is an estrogenic drug. It acts like ethylene estradiol but is 20 times more potent. Combined with progestin-based contraceptives, it has a synergistic effect of inhibiting ovulation, which can enhance contraceptive efficacy and reduce side effects such as breakthrough bleeding. In addition, it can also be used for menstrual disorders such as amenorrhea, hypomenorrhea, menopausal syndrome, and uterine hypoplasia. For use in the preparation of contraceptive pills.

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