5-dibenzoate CAS#122111-01-7

5-dibenzoate, Promotion Season Now in Store and Free Sample for Testing with Factory Price

• Chemical Name:2-difluoro-γ-lactone
• CAS No.:    122111-01-7
• Molecular Fomula: ： C19H14F2O6
• Molecular weight： 376.31
• Appearance: White powder
• Sample：Available

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Description of 2-difluoro-γ-lactone

Bretazenil (Ro16-6028) is an imidazopyrrolobenzodiazepine anxiolytic drug that is derived from the benzodiazepine family and was invented in 1988.
It is most closely related in structure to the benzodiazepine antagonist flumazenil, although its effects are somewhat different. It is classed as a high-potency benzodiazepine due to its high-affinity binding to benzodiazepine binding sites where it acts as a partial agonist. Its profile as a partial agonist and preclinical trial data suggests that it may have a reduced adverse effect profile. In particular, bretazenil has been proposed to cause a less strong development of tolerance and withdrawal syndrome. Bretazenil differs from traditional 1,4-benzodiazepines by being a partial agonist and because it binds to α1, α2, α3, α4, α5, and α6 subunit-containing GABAA receptor benzodiazepine receptor complexes. 1,4-benzodiazepines bind only to α1, α2, α3 and α5 GABAA benzodiazepine receptor complexes.

Basic Info of 5-dibenzoate

Basic Info
Numbering system
Properties
Safety Info
Basic Info

Numbering system

Properties

Safety Info

What is 5-dibenzoate?

With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives. One such product is 5-dibenzoate   which has developed particularly rapidly in recent years. Do you know about 5-dibenzoate  ?

The official answer：2-Deoxy-2,2-difluoropentanose-1-one 3,5-dibenzoate is a synthetic intermediate of gemcitabine hydrochloride. Gemcitabine hydrochloride is a new synthetic difluorinated nucleoside antimetabolic antitumor drug, which was first developed by Eli Lilly and Company, under the trade name of “Jianze”.

What’s the application of 5-dibenzoate?

2-Deoxy-2,2-difluoropentanose-1-one3, a chemical intermediate of2-difluoro-γ-lactone

Conclusion

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