Semax, Promotion Season Now in Store and Free Sample for Testing with Factory Price
Chemical Name: Semax
CAS No.: 80714-61-0
Molecular Fomula: C37H51N9O10S
Molecular weight: 813.92
Appearance: white to tan powderr
Sample: Available
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Description of lemod solu
- Semax is a drug produced and prescribed mostly in Russia and Ukraine for a broad range of conditions but predominantly for its purported nootropic, neuroprotective, and neurogenic/neurorestorative properties. It is a heptapeptide, synthetic analog of a fragment of adrenocorticotropic hormone (ACTH), ACTH (4-10), of the following structure: Met-Glu-His-Phe-Pro-Gly-Pro. Semax has not been evaluated by the U.S. FDA.
- Semax has undergone extensive study in Russia and is on the Russian List of Vital & Essential Drugs approved by the Russian Federation government on December 7, 2011. Medical uses for Semax include treatment of stroke, transient ischemic attack, memory and cognitive disorders, peptic ulcers, optic nerve disease, and to boost the immune system.
- In animals, Semax rapidly elevates the levels and expression of brain-derived neurotrophic factor (BDNF) and its signaling receptor TrkB in the hippocampus, and rapidly activates serotonergic and dopaminergic brain systems.
- In accordance, it has been found to produce antidepressant-like and anxiolytic-like effects, attenuate the behavioral effects of exposure to chronic stress, and potentiate the locomotor activity produced by D-amphetamine. As such, it has been suggested that Semax may be effective in the treatment of depression, as well as in attention deficit hyperactivity disorder (ADHD).
Though the exact mechanism of action of Semax is unclear, there is evidence that it may act through melanocortin receptors. - Specifically, there is a report of Semax competitively antagonizing the action of the melanocortin receptor full agonist α-melanocyte-stimulating hormone (α-MSH) at the MC4 and MC5 receptors in both in vitro and in vivo experimental conditions, indicating that it may act as an antagonist or partial agonist of these receptors.
- Semax did not antagonize α-MSH at the MC3 receptor, though this receptor could still be a target of the drug. As for the MC1 and MC2 receptors, they were not assayed. In addition to actions at receptors, Semax, as well as a related peptide drug, Selank, have been found to inhibit enzymes involved in the degradation of enkephalins and other endogenous regulatory peptides (IC50 = 10 μM), though the clinical significance of this property is uncertain.
Basic Info of Semax
Basic Info
Numbering system
Properties
Basic Info
Chemical Name | L-Methionyl-L-α-glutamylhistidyl-L-phenylalanyl-L-prolylglycyl-L- proline |
CAS No. | 80714-61-0 |
Molecular Formula | C37H51N9O10S |
Molecular Weight | 813.92000 |
PSA | 325.58000 |
LogP | 2.71460 |
Numbering system
UNII | I5FAL2585H |
Properties
Density | 1.391g/cm3 |
Boiling Point | 1335.2ºC at 760 mmHg |
Flash Point | 761.3ºC |
Refractive Index | 1.617 |
What is lemod solu?
- With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives. One such product is Semax which has developed particularly rapidly in recent years. Do you know about Semax?
- The official answer: Brain natriuretic peptide, a member of the natriuretic peptide family secreted mainly by the heart, is a peptide consisting of 32 amino acid residues. It is so named because it was first found in pig brains. It regulates the automatic balance of blood pressure and blood volume and has diuretic effects.
What’s the application of lemod solu?
Semax has been extensively studied in Russia and was approved by the Government of the Russian Federation on December 7, 2011, in the Chemicalbook List of Important and Essential Drugs in Russia. Semax’s medical uses include the treatment of stroke, transient ischemic attacks, memory and cognitive disorders, peptic ulcers, optic nerve disorders, and strengthening the immune system.
Conclusion
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