2-thiothiazolidin, Promotion Season Now in Store and Free Sample for Testing with Factory Price
- Chemical Name: Rhodanine
- CAS No.: 141-84-4
- Molecular Fomula: :C3H3NOS2
- Molecular weight:133.19
- Appearance:Colorless liquid
- Sample:Available
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Description of 2-thiothiazolidin
- Rhodanine is a 5-membered heterocyclic organic compound possessing a thiazolidine core. It was first discovered in 1877 by Marceli Nencki who named it “Rhodaninsaure” in reference to its synthesis from ammonium rhodanide (in modern chemistry ammonium thiocyanate) and chloroacetic acid in water.
Rhodanines can also be prepared by the reaction of carbon disulfide, ammonia, and chloroacetic acid, which proceeds via an intermediate dithiocarbamate.
Some rhodanine derivatives have pharmacological properties; for instance, epalrestat is used to treat diabetic neuropathy. However, most are promiscuous binders with poor selectivity; as a result, this class of compounds is viewed with suspicion by medicinal chemists,
Basic Info of 2-thiothiazolidin
Basic Info
Numbering system
Properties
Safety Info
Basic Info
Chemical Name | 2-sulfanylidene-1,3-thiazolidin-4-one |
Synonyms | 4-oxo-2-thioxo thiazolidine;4-Oxo-2-thioxothiazoline;4-Thiazolidinone,2-thioxo;2-Thioxothiazolidin-4-one;Rhodaninic acid;Expand |
CAS No. | 141-84-4 |
Molecular Formula | C3H3NOS2 |
Molecular Weight | 133.19200 |
PSA | 86.49000 |
LogP | 0.46310 |
Numbering system
EINECS number | 205-505-1 |
BRN number | 110701 |
MDL number | MFCD00005488 |
RTECS number | VI7700000 |
PubChem number | 24851855 |
Properties
Appearance & Physical State | black hygroscopic crystals |
Density | 1.59 g/cm3 |
Boiling Point | 218.2ºC at 760mmHg |
Melting Point | 167-170ºC |
Flash Point | 85.7ºC |
Refractive Index | 1.711 |
Water Solubility | SOLUBLE IN HOT WATER |
Storage Condition | Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. |
Vapor Pressure | 0.128mmHg at 25°C |
Safety Info
RTECS | VI7700000 |
Hazard Class | 6.1(a) |
Safety Statements | S22-S26-S39 |
HS Code | 29341000 |
WGK Germany | 3 |
Packing Group | II |
RIDADR | UN 3288 |
Risk Statements | R22; R41 |
Hazard Codes | Xn |
Signal Word | Danger |
Symbol | GHS05, GHS07 |
Hazard Declaration | H302; H318 |
Caution Statement | P280; P305 + P351 + P338 |
What is Rhodanine?
- With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives. One such product is Rhodanine which has developed particularly rapidly in recent years. Do you know about Rhodanine?
- The official answer:Rhodanine is a chemical with a melting point of 165-169°C(lit.) density 0.868 refractive index 1.5231(estimate) storage conditions -20°C solubility methanol:soluble0.5g/10mL,clear,colorlesstogreenish-yellow Acidity coefficient(pKa)pK(25°)5.52.
What’s the application of Rhodanine?
- Rhodanine is a chemical substance used in the determination of silver by assay and weight analysis, and gallic acid by spectroscopy. Organic synthesis, manufacture of phenylalanine.
Conclusion
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