Protocatechualdehyde CAS# 139-85-5

1,2-Dihydroxy-4-formylbenzene, Promotion Season Now in Store and Free Sample for Testing with Factory Price

• Chemical Name:  Protocatechualdehyde
• CAS No.:     139-85-5
• Molecular Fomula: ： C7H6O3
• Molecular weight：138.12
• Appearance: Colorless flammable liquid
• Sample：Availablee

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Description of 1,2-Dihydroxy-4-formylbenzene

1,2-Dihydroxy-4-formylbenzene is a phenolic aldehyde, a compound released from cork stoppers into wine.
This molecule can be used as a precursor in the vanillin synthesis by biotransformation by cell cultures of Capsicum frutescens, a type of Chili pepper. It is also found in the mushroom Phellinus linteus.

Basic Info of 1,2-Dihydroxy-4-formylbenzene

Basic Info
Numbering system
Properties
Safety Info
Basic Info

Numbering system

Properties

Safety Info

What is Protocatechualdehyde?

• With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives. One such product is Protocatechualdehyde   which has developed particularly rapidly in recent years. Do you know about Protocatechualdehyde  ?
• The official answer：3,4-Dihydroxybenzaldehyde. The largest manufacturer in China, Shanxi Jinjin, has a monthly production capacity of 6 tons. It is prepared from 3,4-methylenedioxybenzaldehyde by the following steps. Add freshly treated phosphorus pentachloride to 3,4-methylenedioxybenzaldehyde in parts. The reaction is very violent at the beginning and needs to be cooled with ice water, while moisture should be prevented from intruding. About half of the strain after adding phosphorus pentachloride slow can no longer be cooled. The amount of phosphorus pentachloride is 3 times (molar) of 3,4-methylenedioxybenzaldehyde. The resulting reaction solution is slowly heated for 1h to release hydrogen chloride, and then the volatiles is extracted under reduced pressure. Then, the reaction product was poured into cold water, and the precipitated emulsified oil layer was left to cure. Then boil slowly for 3h, add activated carbon and filter, the filtrate is concentrated under reduced pressure, cooled to 0°C, and precipitated crystals. Filtered, washed, and recrystallized with water to obtain the finished product.

What’s the application of Protocatechualdehyde?

Used in organic synthesis; pharmaceutical intermediates, can be used to synthesize a variety of antibacterial and anti-inflammatory drugs, with anti-inflammatory and increase the role of coronary blood flow, is the active ingredient in the four seasons green leaf anti-angina, is one of the main active ingredients in the treatment of nephritis of old man’s grass; also used in spice synthesis, with coronary artery dilation, increase coronary blood flow; the role of the heart and peripheral vascular; inhibition of platelet aggregation; antibacterial Anti-inflammatory effect; calcium antagonism; repair damaged venous valves, treatment of varicose veins, an important pharmaceutical intermediate, can be used to synthesize a variety of antibacterial and anti-inflammatory drugs.

Conclusion

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