Pivaloyl chloride Typical Properties

Pivaloyl chloride Usage

Trimethyl acetyl chloride is also called the pivalic acid chloride, is the production of carbamate pesticides azole aphid of intermediates, also is the intermediate of herbicide different well sanzuotong, can be used for synthesis of amides and phenol ester drugs raw materials, used in the production of (hydroxyl) ampicillin, cephalosporins (hydroxyl) ammonia benzyl, cefazolin, double pivalic acyl adrenal and other drugs, in addition,It is also used to synthesize tert-butyl peroxide tert-valerate and so on.

As an acylation reagent, used in the production of ampicillin and cefalexin. Used as pharmaceutical and pesticide intermediates, used in the production of ampicillin, cefazolin antibiotics and other semi-synthetic penicillin and cephalosporin intermediates, also used as pesticide intermediates, photographic materials of organic yellow intermediates.Acylating agent of ammonia, scherff base, pyrrolidone and alcohol.

Pivaloyl chloride Packaging and Shipping

180kg or 200kg/drum or according to your request.

According to customer’s request

Pivaloyl chloride Storage

Store at room temperature and away from light

Synthetic method of Pivaloyl chloride

Silicon tetrachloride is used as the chlorination agent, and trimethyl acetic acid is used as the raw material. In the presence of Lewis acid catalyst, the reaction produces trimethyl acetyl chloride. Using silicon tetrachloride as chlorination agent and trimethyl acetic acid as raw material, trimethyl acetyl chloride is prepared by reaction in the presence of Lewis acid catalyst. The product yield of this method is 76.1%, and the product content is greater than or equal to 95.8%. This method is simple and easy to operate, mild reaction conditions, high product yield and purity, and effectively utilizes the industrial by-product silicon tetrachloride, and the by-product acyloxysilane can provide additional acid chloride, which is a better industrialized production route.