Item | Standard | Result |
Appearance | A white or almost white crystallinepowder | White crystalline powder |
Solubility | Soluble in ethanol and propylene glycol, slightly soluble in methanol, water, almost insoluble in chloroform, acetone, ethyl acetate, n-hexane | Soluble in ethanol and propylene glycol, slightly soluble in methanol, water, almost insoluble in chloroform, acetone, ethylacetate, n-hexane |
Identification | Infrared absorption spectrum consistent with the reference substance | complies |
Organic impurities | ≤1.5% | 0.093% |
Loss on drying | ≤0.5% | 0.2% |
Residue on ignition | ≤0.5% | 0.07% |
Heavy metals | ≤20ppm | complies |
Assay | 97%~103% | 99.8% |
Brand name | Fousi chemical |
25kg/drum
Stored in a dry warehouse at temperature of 2-8°C
Cyclization and chlorination of methyl cyanoacetate give 4-chloro-2,6-diaminopyrimidine, which is then oxidized with perbenzoic acid to obtain 6-amino-1,2-dihydro-1-hydroxy-2- Imino-4-chloropyrimidine (C4H5CIN4O) is finally condensed with hexahydropyridine to prepare minoxidil.