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- Chemical Name: Metformin
- CAS No.: 657-24-9
- Molecular Fomula: ：C4H11N5
- Molecular weight：129.16
- Appearance: white powder
- Sample：Available
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Basic Info ofmelbin
Basic Info
Numbering system
Properties
Basic Info
| Chemical Name | metformin |
| Synonyms | Fluamine;N’-dimethylguanylguanidine;N,N-dimethylimidodicarbonimidic diamide;Diabex;N,N-dimethyl-biguanide;Expand |
| CAS No. | 657-24-9 |
| Molecular Formula | C4H11N5 |
| Molecular Weight | 129.16400 |
| PSA | 88.99000 |
| LogP | 0.25650 |
Numbering system
| UNII | 9100L32L2N |
Properties
| Density | 1.28 g/cm3 |
| Boiling Point | 224.1ºC at 760 mmHg |
| Flash Point | 89.3ºC |
What is Metformin ?
- With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives. One such product is Metformin which has developed particularly rapidly in recent years. Do you know about Metformin?
- The official answer：Metformin is the first-line first choice and full course drug for the treatment of type 2 diabetes, which mainly reduces fasting and postprandial hyperglycemia by increasing the sensitivity of peripheral tissues such as muscle and fat to insulin, increasing glucose uptake and utilization, promoting anaerobic glycolysis, inhibiting hepatic glycogen xenobiotic effect, reducing hepatic glucose output, and inhibiting glucose uptake by intestinal wall cells. In addition, metformin also has weight loss effects and can inhibit cholesterol biosynthesis and storage, reduce triglyceride and total cholesterol levels, improve vascular endothelial cell function and increase blood flow, especially for obese or overweight type 2 diabetic patients, preventing the occurrence and development of diabetic microvascular complications and reduce the incidence of cardiovascular events.
What’s the application of Metformin ?
- Metformin is an oral hypoglycemic agent of the biguanide class. It promotes glucose uptake by adipose tissue, increases anaerobic enzymolysis in muscle tissue, increases glucose utilization, reduces insulin resistance, decreases glucose absorption through the digestive tract, and lowers blood glucose. It is used for adults with non-insulin-dependent diabetes mellitus and partially dependent diabetes mellitus. For most juvenile diabetes mellitus and lean diabetes mellitus that has not been treated with sulfonylureas, this product can also lower blood glucose after application. It can be used in combination with sulfonylurea or insulin to enhance its hypoglycemic effect. The hypoglycemic effect of metformin: The hypoglycemic effect of metformin is accurate, and there is no hypoglycemic reaction compared with sulfonylurea hypoglycemic drugs, and it is effective for both obese and non-obese non-insulin-dependent diabetic patients (NIDDM), and it can reduce their basal blood glucose concentration by ≥20% (generally 2mmol/L or 36mg/dl) for those who are not effective with diet therapy alone. It is effective in reducing basal blood glucose concentration by ≥20% (generally 2mmol/L or 36mg/dl) in people who have failed diet alone. It can improve the oral or intravenous glucose tolerance test, and its hypoglycemic effect is independent of the blood glucose concentration before use, age, disease duration, body weight, and basal insulin level, and is often used in combination with sulfonylurea for patients whose control is unsatisfactory with a sulfonylurea alone, and the combination can reduce blood glucose by more than 20% than sulfonylurea alone, and the combination with insulin can reduce insulin dosage.
Conclusion
Sincere to the customer and in good faith of quality is our forever followed motto. It’s the basement to be a human and do business. We take all responsibility for our products and service sincerely. We are a company integrating R&D, production, and sales. The design, research, and development of pharmaceutical intermediates including more than 330 kinds of pharmaceutical intermediates such as Anti-infectives, Cardiovascular and Cerebrovascular Systems, Digestive System, Santi-tumor, Nervous System, Geriatric Drugs, and Gynecological Drugs. At the same time, we have more than 4,000 factories in strategic cooperation with nearly 50,000 chemical products, so we can provide you with a one-stop purchasing service, which greatly saves customers’ procurement costs and time.
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