Lenalidomide CAS# 191732-72-6

6-dione, Promotion Season Now in Store and Free Sample for Testing with Factory Price

• Chemical Name:  Lenalidomide
• CAS No.:     191732-72-6
• Molecular Fomula: ： C13H13N3O3
• Molecular weight：259.26
• Appearance: white powder
• Sample：Available

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Description of 6-dione

Lenalidomide (trade name Revlimid) is a derivative of thalidomide introduced in 2004.
It was initially intended as a treatment for multiple myeloma, for which thalidomide is an accepted therapeutic treatment. Lenalidomide has also shown efficacy in the class of hematological disorders known as myelodysplastic syndromes (MDS). Along with several other drugs developed in recent years, lenalidomide has significantly improved overall survival in myeloma (which formerly carried a poor prognosis), although toxicity remains an issue for users. It costs $163,381 per year for the average patient.

Basic Info of 6-dione

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Basic Info

Numbering system

Properties

Safety Info

What is Lenalidomide ?

• With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives. One such product is Lenalidomide   which has developed particularly rapidly in recent years. Do you know about Lenalidomide  ?
• The official answer：Lenalidomide (also known as thalidomide) has been used successfully for the treatment of inflammatory diseases and cancer for the past decade, with FDA-approved indications for: combination with dexamethasone for multiple myeloma (MM); and as maintenance therapy after MM that has undergone autologous hematopoietic stem cell transplantation. However, what many patients and friends do not know is that it can also be used in hepatocellular liver cancer.

What’s the application of Lenalidomide ?

Lenalidomide is an immunomodulatory drug, which possesses multiple mechanisms of action. In in vitro studies, lenalidomide has three main effects:1) direct antitumor action 2) inhibition of angiogenesis 3) immunomodulation. In vivo, lenalidomide induces apoptosis of tumor cells directly or indirectly through inhibition of bone marrow stromal cell support, anti-angiogenic and anti-osteolytic effects, and immunomodulatory activity. At the molecular level, lenalidomide has been shown to interact with ubiquitin E3 ligase and target this enzyme to degrade the Ikaros transcription factors IKZF1 and IKZF3.

Conclusion

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