XALATAN, Promotion Season Now in Store and Free Sample for Testing with Factory Price
- Chemical Name: Latanoprost
- CAS No.: 130209-82-4
- Molecular Fomula: :C26H40O5
- Molecular weight:432.59
- Appearance: pale yellow oil
- Sample:Available
Send Inquiry
Download Quotation
Description of XALATAN
Latanoprost eye solution is a medication administered into the eyes to control the progression of glaucoma or ocular hypertension by reducing intraocular pressure (IOP). It is a prostaglandin analogue (more specifically an analogue of prostaglandin F2α) that lowers the pressure by increasing the outflow of aqueous fluid from the eyes through the uveoscleral tract. Latanoprost is an isopropyl ester prodrug, meaning it is inactive until it is hydrolyzed by esterases in the cornea to the biologically active acid.
Latanoprost was invented by Johan W. Stjernschantz and Bahram Resul, employees of the Pharmacia Corporation of Uppsala, Sweden. It is on the World Health Organization’s List of Essential Medicines, a list of the most important medication needed in a basic health system. It is also known by the brand name of Xalatan manufactured by Pfizer. Annual sales are approximately $1.6 billion. The patent for latanoprost expired in March 2011, and at least one generic version is now widely available in the U.S.
Basic Info of Latanoprost
Basic Info
Numbering system
Properties
Safety Info
Basic Info
Chemical Name | latanoprost |
Synonyms | xa41;LATANAPROST;Lata prostaglandin;Xalata;XALATAN;Expand |
CAS No. | 130209-82-4 |
Molecular Formula | C26H40O5 |
Molecular Weight | 432.59300 |
PSA | 86.99000 |
LogP | 4.18640 |
Numbering system
UNII | 6Z5B6HVF6O |
Properties
Appearance & Physical State | pale yellow oil |
Density | 1.093 g/cm3 |
Boiling Point | 583.8ºC at 760 mmHg |
Flash Point | 188.3ºC |
Refractive Index | 1.537 |
Storage Condition | -20ºC |
Safety Info
RTECS | MJ9669550 |
HS Code | 2937500000 |
WGK Germany | 3 |
What is Latanoprost?
- With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives. One such product is Latanoprost which has developed particularly rapidly in recent years. Do you know about Latanoprost ?
- The official answer:Latanoprost is a prostaglandin. PGF2α prostaglandins and prostaglandin analogs typically have two hydroxyl groups, which are in the cis configuration with respect to each other in the cyclopentane ring, and two side chains in the trans configuration with respect to each other, each with a double bond. groups along the side chain. In addition, in some PGF2α analogs, the side chain carboxylic acid can be esterified. Latanoprost has a saturated side chain of PGF2α in which the carboxylic acid group is esterified, and this compound is used clinically to reduce excessive intraocular pressure in patients with open-angle glaucoma and ocular hypertension.
What’s the application of Latanoprost?
- Latanoprost (trade name: Silyta) is a new anti-glaucoma drug indicated for the topical treatment of primary open-angle glaucoma and ocular hypertension that is difficult to treat or tolerate with other drugs. It is also effective in pigmented glaucoma, atrial angle recession, chronic angle-closure glaucoma, resting uveitis, and epidermal exfoliation syndrome, but not inactive uveitis. Latanoprost is a derivative of prostaglandin F2α, a selective F2α receptor agonist. It is an inactive but rapidly penetrating substance that is hydrolyzed to active free acid in the cornea and plasma. It can increase the outflow of atrial fluid through the corneal layer of the eye, the dosage is small, but it promotes the filling of atrial fluid, and the fluid can penetrate into the suprachoroidal layer of the eye, which has a good effect on lowering intraocular pressure. It also opens up the sieve of the trabecular structure of the eye, which is usually blocked in patients with glaucoma.
Conclusion
Sincere to the customer and in good faith of quality is our forever followed motto. It’s the basement to be a human and do business. We take all responsibility for our products and service sincerely. We are a company integrating R&D, production, and sales. The design, research, and development of pharmaceutical intermediates including more than 330 kinds of pharmaceutical intermediates such as Anti-infectives, Cardiovascular and Cerebrovascular Systems, Digestive System, Santi-tumor, Nervous System, Geriatric Drugs, and Gynecological Drugs. At the same time, we have more than 4,000 factories in strategic cooperation with nearly 50,000 chemical products, so we can provide you with a one-stop purchasing service, which greatly saves customers’ procurement costs and time.
Keywords of Latanoprost
XALATAN , 130209-82-4, buy XALATAN, XALATAN supplier, purchase XALATAN, XALATAN cost, XALATAN manufacturer, order BXALATAN, high pur XALATAN XALATAN