Ivermectin CAS# 70288-86-7

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• Chemical Name:  Ivermectin
• CAS No.:     70288-86-7
• Molecular Fomula: C48H74O14
• Molecular weight：875.09
• Appearance: white powder
• Sample：Available

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Description of IVOMEC

Ivermectin is a medication that is effective against many types of parasites. It is used to treat head lice, scabies, river blindness, strongyloidiasis, and lymphatic filariasis, among others. It can be either applied to the skin or taken by mouth. The eyes should be avoided.
Common side effects include red eyes, dry skin, and burning skin. It is unclear if it is safe for use during pregnancy, but is likely acceptable for use during breastfeeding. It is in the avermectin family of medications and works by causing an increase in permeability of cell membrane resulting in paralysis and death of the parasite.
Ivermectin was discovered in 1975 and came into medical use in 1981. It is on the World Health Organization’s List of Essential Medicines, the most important medications needed in a basic health system. The wholesale cost in the developing world is about US$0.12 for a course of treatment. In the United States it costs $25–50. In other animals it is used to prevent and treat heartworm among other diseases.

Basic Info of IVOMEC

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Basic Info

Numbering system

Properties

Safety Info

What is Ivermectin ?

• With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives. One such product is Ivermectin   which has developed particularly rapidly in recent years. Do you know about Ivermectin  ?
• The official answer：Ivermectin is a new type of highly effective semi-synthetic antibiotic insecticide, acaricide and nematicide, which is an insect neurotoxin agent and biological penetrant. The mechanism of action is to interfere with the pest’s neurophysiological activities, stimulate the release of γ-aminobutyric acid, which acts on the nerve and muscle joints, increasing the release of chloride ions and inhibiting the transmission of information from the nerve joints, resulting in paralysis and poisoning death of pests and pest mites. Its product is colorless or light brownish-yellow liquid. Ivermectin is a new type of broad-spectrum, high-efficiency, low-toxicity antibiotic anti-parasitic drug, which has a good repellent effect on internal and external parasites, especially nematodes and arthropods. However, it is not effective against cestodes, trematodes, and protozoa. The anthelmintic effect of macrolide antiparasitics on nematodes and arthropods lies in increasing the release of the inhibitory transmitter γ-aminobutyric acid (GABA) from the worm, as well as opening the glutamate-controlled Cl ion channel, enhancing the permeability of the nerve membrane to Cl, thus blocking the transmission of nerve signals and eventually nerve paralysis, causing muscle cells to lose the ability to contract, thus leading to the death of the worm.

What’s the application of Ivermectin ?

• Effective in the treatment and control of onchocerciasis, with lower adverse effects than ethamazine. Uses Anti-parasitic agent with anthelmintic activity against nematodes, hookworms, roundworms, helminths, insects, and mites

Conclusion

Sincere to the customer and in good faith of quality is our forever followed motto. It’s the basement to be a human and do business. We take all responsibility for our products and service sincerely. We are a company integrating R&D, production, and sales. The design, research, and development of pharmaceutical intermediates including more than 330 kinds of pharmaceutical intermediates such as Anti-infectives, Cardiovascular and Cerebrovascular Systems, Digestive System, Santi-tumor, Nervous System, Geriatric Drugs, and Gynecological Drugs. At the same time, we have more than 4,000 factories in strategic cooperation with nearly 50,000 chemical products, so we can provide you with a one-stop purchasing service, which greatly saves customers’ procurement costs and time.

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