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- Chemical Name: Iodixanol
- CAS No.: 92339-11-2
- Molecular Fomula:C35H44I6N6O15
- Molecular weight：1550.18
- Appearance: white solid
- Sample：Available
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Description of Acupaque
Iodixanol is a contrast agent, sold under the trade name Visipaque; it is also sold as a density gradient medium under the name OptiPrep. Visipaque is commonly used as a contrast agent during coronary angiography. It is the only iso-osmolar contrast agent, with an osmolality of 290 mOsm/kg H2O, the same as blood. It is sold in 2 main concentrations 270 mgI/ml and 320 mgI/ml – hence the name Visipaque 270 or 320. It is sold in single dose units and a large 500ml plastic bottle for multi-dose dispensing; It was originally made by Nycomed, which then merged with Amersham which finally was bought by Jeff Immelt to become GE Healthcare. The majority of Visipaque is made in Cork, Ireland, with additional plants in China and Oslo. All Iodixanol bulk powder is made in Norway by Axis-Shield and shipped to the various plants for final manufacture (distributed in the United States by Cosmo Bio USA).
A very similar product also manufactured by GE Healthcare is Omnipaque (Iohexol as the main drug substance).
Basic Info of Acupaque
Basic Info
Numbering system
Properties
Safety Info
Basic Info
| Chemical Name | iodixanol |
| Synonyms | 1,3-bis(acetylamino)-N,N’-bis[3,5-bis(2,3-dihydroxypropylaminocarbonyl)-2,4,6-triiodophenyl]-2-hydroxypropane;Iodixanolum [Latin];Visipaque;Indixanol;3,3′,5,5′-tetrakis(2,3-dihydroxypropylcarbamoyl)-2,2′,4,4′,6,6′-hexaiodo-N,N’-(2-hydroxypropane-1,3-diyl)diacetanilide;Expand |
| CAS No. | 92339-11-2 |
| Molecular Formula | C35H44I6N6O15 |
| Molecular Weight | 1550.18000 |
| PSA | 339.09000 |
| LogP | -0.02330 |
Numbering system
| UNII | HW8W27HTXX |
Properties
| Appearance & Physical State | off-white to white powder |
| Density | 2.295 g/cm3 |
| Boiling Point | 1250.9ºC at 760 mmHg |
| Melting Point | 262-267ºC (dec.) |
| Flash Point | 710.3ºC |
| Refractive Index | 1.751 |
| Stability | Stable and nont reactive. |
| Storage Condition | Store in original container according to temperature stated on container and in package insert. |
Safety Info
| HS Code | 2924299090 |
What is Iodixanol?
- With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives. One such product is Iodixanol which has developed particularly rapidly in recent years. Do you know about Iodixanol ?
- The official answer：Melting point 240~250℃. Soluble in water. Viscosity (37℃) 11.1mPa?s; pH 7.2~7.6 (C=320mgI/m1). 50% aqueous solution (W/V): viscosity 8.3mPa?s; n1.4128±0.0003; d1.266±0.003. Acute toxicity LD50 mice (mg/kg): 21 intravenous injection.
What’s the application of Iodixanol?
- Iodixanol (Iodixanol), chemically known as 5,5′-((2-hydroxy-1,3-propane)bis(acetylimino))bis(N,N’-bis(2,3 -dihydroxypropyl)-2,4,6-triiodo-1,3-benzenedicarboxamide, developed by Nycomed, Norway, is a new non-ionic X-ray contrast agent (osmolarity of 290mosmol/kg), the only contrast agent that is isotonic with plasma when applied intravascularly, non-ionic X-ray contrast agent. UsesX – ray contrast agent. It is used for cardiovascular angiography, cerebral angiography (conventional with i.a. DSA), peripheral arteriography (conventional with i.a. DSA), abdominal angiography (i.a. DSA), urography, venography and CT-enhanced examination in adults.
Conclusion
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