Dexzopiclone, Promotion Season Now in Store and Free Sample for Testing with Factory Price
- Chemical Name: Eszopiclone
- CAS No.: 138729-47-2
- Molecular Fomula: :C17H17ClN6O3
- Molecular weight:388.81
- Appearance: White powder
- Sample:Available
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Description of Dexzopiclone
Eszopiclone, marketed by Sunovion under the brand-name Lunesta, is a nonbenzodiazepine hypnotic which is slightly effective for insomnia. Eszopiclone is the active dextrorotatory stereoisomer of zopiclone, and belongs to the class of drugs known as cyclopyrrolones.
Eszopiclone (Lunesta) along with other “Z-drugs” including zolpidem (Ambien), zaleplon (Sonata) are the most commonly prescribed sedative hypnotics in the United States. Eszopiclone is not marketed in the European Union following a 2009 decision by the EMA denying it new active substance status, in which it ruled that eszopiclone was too similar to zopiclone to be considered a new patentable product.
Eszopiclone is now available in a generic form in the United States as of May 2014. On May 15, 2014, the USFDA asked that the starting dose of Eszopiclone (Lunesta) be lowered from 2 milligrams to 1 milligram after it was observed in a study that even 8 hours after taking the drug at night, some patients were not able to cope with their next-day activities like driving and other activities that require full alertness.
Basic Info of Dexzopiclone
Basic Info
Numbering system
Properties
Safety Info
Basic Info
Chemical Name | eszopiclone |
Synonyms | Estorra;Esopiclone;UNII-UZX80K71OE;[(7S)-6-(5-chloropyridin-2-yl)-5-oxo-7H-pyrrolo[3,4-b]pyrazin-7-yl] 4-methylpiperazine-1-carboxylate;Eszopiclone;Expand |
CAS No. | 138729-47-2 |
Molecular Formula | C17H17ClN6O3 |
Molecular Weight | 388.80800 |
PSA | 91.76000 |
LogP | 1.50880 |
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Numbering system
MDL number | MFCD03700720 |
Properties
Appearance & Physical State | White or slightly yellowish powder |
Density | 1.54 g/cm3 |
Boiling Point | 580.7ºC at 760 mmHg |
Melting Point | 202-204ºC |
Flash Point | 305ºC |
Refractive Index | 1.688 |
Vapor Pressure | 1.78E-13mmHg at 25°C |
Safety Info
Safety Statements | S26-S36 |
HS Code | 2933599090 |
Risk Statements | R20/21/22; R36/37/38; R62 |
Hazard Codes | Xn |
What is Eszopiclone?
- With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives. One such product is Eszopiclone which has developed particularly rapidly in recent years. Do you know about Eszopiclone ?
- The official answer:Dexzopiclone is a new fast-acting, short-acting, non-benzodiazepine sedative-hypnotic developed by Sepracor, Inc. and is the dextro-monoisomer of zopiclone. It is approved by the U.S. Food and Drug Administration for the treatment of people with insomnia, difficulty falling asleep, or difficulty maintaining sleep. The pharmacokinetics of dexrazopiclone and zopiclone are similar. After a single oral dose of 1, 2, or 3 mg of dexzopiclone in healthy subjects (6 subjects per group), absorption was rapid and complete, with a peak time of 1.0 to 1.5 hours. The plasma half-life was 6 hours. The “Digit Symbol Substitution Test (DSST)” assessed psychomotor impairment in subjects, and the Sanford Sleep Scale (SSS) assessed daytime sleepiness to observe the relationship between pharmacokinetic characteristics and pharmacodynamics, and no psychomotor impairment was observed in any of the three-dose groups after a single 6-hour oral dose of the drug, or daytime drowsiness.
What’s the application of Eszopiclone?
Dexzopiclone is a chemical used as a sedative-hypnotic in the treatment of people with insomnia, difficulty falling asleep, or difficulty maintaining sleep.
Conclusion
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