Epothilone D, Promotion Season Now in Store and Free Sample for Testing with Factory Price
- Chemical Name: Epothilone D
- CAS No.: 189453-10-9
- Molecular Fomula: : C27H41NO5S
- Molecular weight: 491.68
- Appearance: White Solid
- Sample:Available
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Description of Epothilone D
Epothilones are polyketide natural products that inhibit cancer cells by a mechanism similar to paclitaxel, and also are effective against paclitaxel-resistant tumours. Epothilone D is in phase I clinical testing of in patients with advanced solid tumours. Epothilone D is a cytotoxic macrolide that stabilises malignant cells’ microtubules and arrests mitosis, a characteristic it shares with other epothilones. They bind to the same hepatic sites as does paclitaxel (Taxol) in a 1:1 stoichiometric ratio of a, b-tubulin heterodimers.
Basic Info of Epothilone D
Basic Info
Numbering system
Basic Info
Chemical Name | epothilone D |
Synonyms | Epothilone D;Epo A;desoxyepothilone B;epithilone A;Epothilones;Expand |
CAS No. | 189453-10-9 |
Molecular Formula | C26H39NO5S |
Molecular Weight | 477.65700 |
PSA | 124.96000 |
LogP | 4.87620 |
Numbering system
UNII | T0358E0YUF |
What is Epothilone D?
- With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives. One such product is Epothilone D which has developed particularly rapidly in recent years. Do you know about Epothilone D ?
- The official answer:Epothilones are macrolide secondary metabolites produced by Mucor fibrosis. Its mechanism of action is the same as that of paclitaxel, which inhibits the proliferation of tumor cells by promoting microtubule aggregation, and compared with paclitaxel, Epothilones have the advantage of less toxicity, better water solubility, stronger effect on paclitaxel-resistant cells, and broader anti-tumor spectrum, etc. It is one of the most promising new anti-tumor drugs, and currently has remarkable effects on the treatment of colon, breast, and ovarian cancers.
What’s the application of Epothilone D?
Ebolomycin is a chemical used in the treatment of colon, breast, and ovarian cancers.
The overview, preparation method, and application of Ebolomycin B is compiled by Ding Hong of (2015-12-21)
Conclusion
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