diclofurazol, Promotion Season Now in Store and Free Sample for Testing with Factory Price
- Chemical Name: Diloxanide furoate
- CAS No.: 3736-81-0
- Molecular Fomula: ：C14H11Cl2NO4
- Molecular weight：328.15
- Appearance:white powder
- Sample：Available
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Description of diclofurazol
Diloxanide (INN) is a luminal amebicide used in the treatment of amebiasis. It is formulated as the furoate ester diloxanide furoate. It is considered the luminal agent of choice for mild intestinal amebiasis or asymptomatic cyst carriers. It can also be added to metronidazole (active drug in luminal and extraintestinal amebiasis) in acute amebic dysentery as well as hepatic abscess(In hepatic abscess it is for the control of cysts in the lumen which may cause relapse). The drug was discovered by The Boots Company Plc in 1956 and introduced as Furamide. The Furamide brand is now owned by Abbott Laboratories. It is not available in the United States. In India it is available as Amicline by Franco-Indian.
Diloxanide furoate is on the World Health Organization’s List of Essential Medicines, a list of the most important medication needed in a basic health system.
Basic Info of diclofurazol
Basic Info
Numbering system
Properties
Basic Info
| Chemical Name | [4-[(2,2-dichloroacetyl)-methylamino]phenyl] furan-2-carboxylate |
| Synonyms | Amebiazol;Histomibal;Furentomin;Diclofurazol;Entamide furoate;Expand |
| CAS No. | 3736-81-0 |
| Molecular Formula | C14H11Cl2NO4 |
| Molecular Weight | 328.14700 |
| PSA | 59.75000 |
| LogP | 3.26530 |
Numbering system
| UNII | YP4N72IW34 |
Properties
| Safety Statements | S36 |
| Risk Statements | R22 |
What is Diloxanide furoate?
- With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives. One such product is Diloxanide furoate which has developed particularly rapidly in recent years. Do you know about Diloxanide furoate?
- The official answer：Diloxanidefuroate is a prodrug of dibenzoxanide.Diloxanidefuroate is a potent antiprotozoal agent with oral activity (anti-protozoal agent) for studies related to amoebiasis, mild intestinal amoebiasis, or asymptomatic encapsulated bacterial infections. Melting point 111-114°CBoiling point 438.4±45.0°C(Predicted)Density1.424±0.06g/cm3(Predicted)Storage conditionsSealedindry,2-8°CAcidity coefficient(pKa)-0?+-.0.50(Predicted)
What’s the application of Diloxanide furoate?
- It is a pharmaceutical chemical, dichloronitrate furoate, which kills amoebas directly and is effective against both intestinal and extraintestinal amoebas, and can be used in combination with emetine or chloroquine. It is the drug of choice for the treatment of asymptomatic people with amoebic encapsulation.
Conclusion
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