2H-1-BENZOPYAN-2-ONE, Promotion Season Now in Store and Free Sample for Testing with Factory Price
- Chemical Name: Coumarin
- CAS No.: 91-64-5
- Molecular Fomula: :C9H6O2
- Molecular weight:146.14
- Appearance:White crystals
- Sample:Available
Send Inquiry
Download Quotation
Description of 2H-1-BENZOPYAN-2-ONE
- 2H-1-BENZOPYAN-2-ONE (2H-chromen-2-one) is a fragrant organic chemical compound in the benzopyrone chemical class, which is a colorless crystalline substance in its standard state. It is a natural substance found in many plants.
The name comes from a French term for the tonka bean, coumarou, one of the sources from which 2H-1-BENZOPYAN-2-ONE was first isolated as a natural product in 1820. It has a sweet odor, readily recognised as the scent of new-mown hay, and has been used in perfumes since 1882. Sweet woodruff, Meadowsweet, sweet grass and sweet-clover in particular are named for their sweet (i.e., pleasant) smell, which in turn is due to their high 2H-1-BENZOPYAN-2-ONE content. When it occurs in high concentrations in forage plants, 2H-1-BENZOPYAN-2-ONE is a somewhat bitter-tasting appetite suppressant, and is presumed to be produced by plants as a defense chemical to discourage predation.
2H-1-BENZOPYAN-2-ONE is used in certain perfumes and fabric conditioners. 2H-1-BENZOPYAN-2-ONE has been used as an aroma enhancer in pipe tobaccos and certain alcoholic drinks, although in general it is banned as a flavorant food additive, due to concerns regarding its hepatotoxicity in animal models.
2H-1-BENZOPYAN-2-ONE was first synthesized in 1868. It is used in the pharmaceutical industry as a precursor reagent in the synthesis of a number of synthetic anticoagulant pharmaceuticals similar to dicoumarol, the notable ones being warfarin (brand name Coumadin) and some even more potent rodenticides that work by the same anticoagulant mechanism. So-called “2H-1-BENZOPYAN-2-ONEs” (modified 2H-1-BENZOPYAN-2-ONEs) are a type of vitamin K antagonists. Pharmaceutical (modified) 2H-1-BENZOPYAN-2-ONEs were all developed from the study of sweet clover disease; see warfarin for this history. However, unmodified 2H-1-BENZOPYAN-2-ONE itself, as it occurs in plants, has no effect on the vitamin K coagulation system, or on the action of warfarin-type drugs.
2H-1-BENZOPYAN-2-ONE has clinical medical value by itself, as an edema modifier. 2H-1-BENZOPYAN-2-ONE and other benzopyrones, such as 5,6-benzopyrone, 1,2-benzopyrone, diosmin, and others, are known to stimulate macrophages to degrade extracellular albumin, allowing faster resorption of edematous fluids. Other biological activities that may lead to other medical uses have been suggested, with varying degrees of evidence.
2H-1-BENZOPYAN-2-ONE is also used as a gain medium in some dye lasers, and as a sensitizer in older photovoltaic technologies.
Basic Info of 2H-1-BENZOPYAN-2-ONE
Basic Info
Numbering system
Properties
Safety Info
Basic Info
Chemical Name | 2H-1-BENZOPYAN-2-ONE |
Synonyms | Rattex;Kumarin;2H-1-Benzopyran-2-one;chromen-2-one;2H-1-BENZOPYAN-2-ONEE;Expand |
CAS No. | 91-64-5 |
Molecular Formula | C9H6O2 |
Molecular Weight | 146.14300 |
PSA | 30.21000 |
LogP | 1.79300 |
Numbering system
MDL number | MFCD00006850 |
EINECS number | 202-086-7 |
Properties
Appearance & Physical State | white crystalline solid |
Density | 0.935 |
Boiling Point | 298ºC |
Melting Point | 68-71ºC |
Flash Point | 162ºC |
Refractive Index | 1.594 |
Water Solubility | 1.7 g/L (20 ºC) |
Storage Condition | Refrigerator |
Vapor Pressure | 0.01 mm Hg ( 47 °C) |
Safety Info
RTECS | GN4200000 |
Hazard Class | 6.1 |
Safety Statements | S26-S36/37 |
HS Code | 2932999099 |
WGK Germany | 1 |
Packing Group | III |
RIDADR | UN 2811 6.1/PG 3 |
Risk Statements | R20/21/22; R36/37/38; R40 |
Hazard Codes | Xn |
What is Coumarin?
- With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives. One such product is Coumarin which has developed particularly rapidly in recent years. Do you know about Coumarin?
- The official answer:White crystals with sublimation, the aroma of lemongrass, and a slightly medicinal fragrance. Insoluble in cold water, soluble in hot water, ethanol, ether, chloroform.
What’s the application of Coumarin?
- It is used in the manufacture of fragrances, as a scent fixing agent, and also for electroplating industrial applications Coumarin was discovered in 1820 in black coumarin. Coumarin is found in many plants in the form of glycosides. It has the strong fragrance of black coumarin, but also has the sweet aroma of freshly mown grass and chocolate, with a long-lasting fragrance. The aroma of fresh hay is largely due to the production and release of coumarin during the fermentation and decomposition of glycosides during the drying of freshly mown grass. Coumarin is used in the manufacture of fragrances. It is commonly used in the formulation of freshly mown grass and fuchsias. It is also used in fragrances such as violet, sunflower, orchid, hawthorn, orchid, and lavender. It and vanillin together can be used in candy, pastry, and another flavoring, added to tobacco can increase the natural flavor. Adding coumarin to galvanizing (or cadmium, nickel) plating solution can reduce the plating pore and increase the brightness. Coumarin is a raw material for the manufacture of other fragrances and many other chemicals. Coumarin is the parent of a large group of derivatives. Some of these derivatives are found in nature, while others are produced by synthetic methods. Used in the manufacture of fragrances and soaps for fluorescent indicator purposes.
Conclusion
Sincere to the customer and in good faith of quality is our forever followed motto. It’s the basement to be a human and do business. We take all responsibility for our products and service sincerely. We are a company integrating R&D, production, and sales. The design, research, and development of pharmaceutical intermediates including more than 330 kinds of pharmaceutical intermediates such as Anti-infectives, Cardiovascular and Cerebrovascular Systems, Digestive System, Santi-tumor, Nervous System, Geriatric Drugs, and Gynecological Drugs. At the same time, we have more than 4,000 factories in strategic cooperation with nearly 50,000 chemical products, so we can provide you with a one-stop purchasing service, which greatly saves customers’ procurement costs and time.
Keywords of Coumarin
2H-1-BENZOPYAN-2-ONE , 91-64-5, buy 2H-1-BENZOPYAN-2-ONE, 2H-1-BENZOPYAN-2-ONE supplier, purchase 2H-1-BENZOPYAN-2-ONE, 2H-1-BENZOPYAN-2-ONE cost, 2H-1-BENZOPYAN-2-ONE manufacturer, order 2H-1-BENZOPYAN-2-ONE, high pur 2H-1-BENZOPYAN-2-ONE 2H-1-BENZOPYAN-2-ONE