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- Chemical Name: Calcium dobesilate
- CAS No.: 20123-80-2
- Molecular Fomula: : 2C6H5O5S
- Molecular weight:418.41
- Appearance: white poewder
- Sample:Available
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Basic Info of doxium
Basic Info
Numbering system
Properties
Safety Info
Basic Info
Chemical Name | calcium,2,5-dihydroxybenzenesulfonate |
Synonyms | Nugatex;Calcium dobesilate;calcium 2,5-dihydroxybenzenesulfonate;Dobesilat-Calciumsalz;Dobesilato calcico;Expand |
CAS No. | 20123-80-2 |
Molecular Formula | C12H10CaO10S2 |
Molecular Weight | 418.41000 |
PSA | 212.08000 |
LogP | 2.16540 |
Numbering system
MDL number | MFCD00867249 |
Properties
Appearance & Physical State | white or almost powder |
Safety Info
HS Code | 2924299090 |
Hazard Declaration | H315; H319; H335 |
Caution Statement | P261; P305 + P351 + P338 |
Signal Word | Warning |
Symbol | GHS07 |
What is Calcium dobesilate?
- With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives. One such product is Calcium dobesilate which has developed particularly rapidly in recent years. Do you know about Calcium dobesilate ?
- The official answer:Calcium Dobesilate acts on the endothelial cell layer and basal layer of capillary blood vessels, regulates and improves capillary permeability and flexibility, increases the resistance of capillary walls, reduces their permeability, has an activating effect on the lymphatic circulation system, reduces blood and plasma viscosity, corrects the albumin/globulin ratio, reduces platelet hyper aggregation, and reduces plasma viscosity, thus preventing thrombosis. In addition, it can also inhibit the production of sorbitol (the mechanism of action in the treatment of diabetic retinopathy) and promote the formation of collagen fibers, the main component of the arterial wall.
What’s the application of Calcium dobesilate?
- Calcium hydroxybenzenesulfonate inhibits the hyperpermeability of microvessels caused by vasoactive substances (histamine, 5-hydroxytryptamine, bradykinin, hyaluronidase, prostaglandin), reduces intimal damage, improves collagen biosynthesis in the basement membrane, improves capillary wall permeability, increases the flexibility of red blood cells, reduces blood viscosity, improves lymphatic reflux, and thus reduces pathological hyperpermeability of microvascular walls. 2. Calcium hydroxybenzenesulfonate can reduce the level of fibrinogen and globulin, reduce the hyper aggregation of red blood cells, activate fibrinase activity, increase the lysis capacity of blood fibrin, thus reducing the viscosity of blood. Reduce the synthesis and release of platelet aggregation factors, inhibit a variety of aggregation factors, cause aggregation reaction and platelet spontaneous aggregation, reduce platelet activity, prevent thrombosis, its effect is dose-related. 3. For microvascular lesions, calcium hydroxybenzenesulfonate can increase the caliber of fine arteries and fine veins, increase the number of capillary openings, significantly accelerate blood flow, and significantly improve the effect of microcirculation. Eliminate or relieve edema, capillary oozing, heaviness, and pressure feeling of lower limbs.4. Calcium hydroxybenzenesulfonate significantly reduce the content of sorbitol, blocks the channel of sugar to sorbitol, and inhibits the dysfunction caused by increased sorbitol in blood cells.
Conclusion
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