Bestatin, Promotion Season Now in Store and Free Sample for Testing with Factory Price
Chemical Name: Bestatin
CAS No.: 58970-76-6
Molecular Fomula: C16H24N2O4
Molecular weight: 308.37
Appearance: White Powder
Sample: Available
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Description of nk421
Ubenimex (INN), also known more commonly as bestatin, is a competitive, reversible protease inhibitor. It is an inhibitor of arginyl aminopeptidase (aminopeptidase B), leukotriene A4 hydrolase (a zinc metalloprotease that displays both epoxide hydrolase and aminopeptidase activities), alanyl aminopeptidase (aminopeptidase M/N), leucyl/cystinyl aminopeptidase (oxytocinase/vasopressinase), and membrane dipeptidase (leukotriene D4 hydrolase). It is being studied for use in the treatment of acute myelocytic leukemia. It is derived from Streptomyces olivoreticuli. Ubenimex has been found to inhibit the enzymatic degradation of oxytocin, vasopressin, enkephalins, and various other peptides and compounds.
Basic Info of nk421
Basic Info
Numbering system
Properties
Safety Info
Basic Info
Chemical Name | Ubenimex |
CAS No. | 58970-76-6 |
Molecular Formula | C16H24N2O4 |
Molecular Weight | 308.37300 |
PSA | 112.65000 |
LogP | 1.62400 |
Numbering system
UNII | I0J33N5627 |
Properties
Appearance & Physical State | White crystalline powder |
Density | 1.197 g/cm3 |
Boiling Point | 604.7ºC at 760 mmHg |
Melting Point | 245ºC |
Flash Point | 319.5ºC |
Refractive Index | 1.557 |
Stability | Stable at normal temperatures and pressures. |
Storage Condition | 2-8ºC |
Safety Info
RTECS | OH2915000 |
Safety Statements | S24/25 |
WGK Germany | 3 |
What is nk421?
- With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives. One such product is Bestatin which has developed particularly rapidly in recent years. Do you know about Bestatin?
- The official answer: Ubenimex (I Ubenimex; NN), also known as bestatin, with the chemical formula N-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanoyl]-L-leucine; is a competitive, reversible protease inhibitor. It inhibits arginyl aminopeptidase (aminopeptidase B), leukotriene A4 hydrolase (zinc metalloprotease showing epoxide hydrolase and aminopeptidase activity), alanyl aminopeptidase (aminopeptidase M/N), and leucyl/cystamylaminopeptidase (cathepsin/vasopressinase) (leukotriene D4 hydrolase). It is being investigated for the treatment of acute myeloid leukaemia. It is derived from Streptomyces olivoreticuli. Ubenimex has been found to inhibit the enzymatic degradation of oxytocin, pressing, enkephalin and various other peptides and compounds
What’s the application of nk421?
It can enhance the immune function and is used for adjuvant treatment of anti-cancer chemotherapy and radiotherapy, age-related immune function deficiency, etc. It can be used with chemotherapy, radiotherapy and combined application in patients with leukaemia, multiple myeloma, myelodysplastic syndrome and after hematopoietic stem cell transplantation, as well as other solid tumours.
Conclusion
Sincere to the customer and in good faith of quality is our forever followed motto. It’s the basement to be a human and do business. We take all responsibility for our products and service sincerely. We are a company integrating R&D, production, and sales. The design, research, and development of pharmaceutical intermediates including more than 330 kinds of pharmaceutical intermediates such as Anti-infectives, Cardiovascular and Cerebrovascular Systems, Digestive System, Santi-tumor, Nervous System, Geriatric Drugs, and Gynecological Drugs. At the same time, we have more than 4,000 factories in strategic cooperation with nearly 50,000 chemical products, so we can provide you with a one-stop purchasing service, which greatly saves customers’ procurement costs and time.
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