1,3-benzenediacetonitrile, Promotion Season Now in Store and Free Sample for Testing with Factory Price
- Chemical Name: Anastrozole
- CAS No.: 120511-73-1
- Molecular Fomula: :C17H19N5
- Molecular weight:293.37
- Appearance:white solid
- Sample:Available
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Description of 1,3-benzenediacetonitrile
Anastrozole (INN) (marketed under the trade name Arimidex by AstraZeneca) is a non-steroidal aromatase-inhibiting drug approved for treatment of breast cancer after surgery, as well as for metastasis in both pre and post-menopausal women. The severity of breast cancer can be increased by estrogen, as sex hormones cause hyperplasia, and differentiation at estrogen receptor sites. Anastrozole works by inhibiting the synthesis of estrogen. The patent on Arimidex by AstraZeneca expired June 2010.
It is on the World Health Organization’s List of Essential Medicines, a list of the most important medications needed in a basic health system.
Basic Info of 1,3-benzenediacetonitrile
Basic Info
Numbering system
Properties
Safety Info
Basic Info
Chemical Name | anastrozole |
Synonyms | ICI-D-1033;Anastrozole;ZD-1033;Anastrol;1,3-benzenediacetonitrile;Expand |
CAS No. | 120511-73-1 |
Molecular Formula | C17H19N5 |
Molecular Weight | 293.36600 |
PSA | 78.29000 |
LogP | 2.92876 |
Numbering system
RTECS number | CZ1465000 |
Properties
Appearance & Physical State | crystalline solid |
Density | 1.08 g/cm3 |
Boiling Point | 469.7ºC at 760 mmHg |
Melting Point | 81-82ºC |
Refractive Index | 1.791 |
Storage Condition | Store in original container in a cool dark place. |
Safety Info
Hazard Class | 6.1(b) |
Safety Statements | S26; S37/39 |
HS Code | 2933990090 |
Packing Group | III |
RIDADR | 3249 |
Risk Statements | R36/37/38 |
Hazard Codes | Xi |
What is Anastrozole?
- With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives. One such product is Anastrozole which has developed particularly rapidly in recent years. Do you know about Anastrozole ?
- The official answer:Anastrozole is a potent and selective triazole aromatase inhibitor that inhibits cytochrome P-450-dependent aromatase and thus blocks estrogen biosynthesis, which is the main stimulus for breast cancer cell growth. Letrozole is indicated for the treatment of advanced postmenopausal breast cancer and is mostly used as second-line therapy after failure of anti-estrogen therapy. Anastrozole is effective in reducing the risk of breast cancer recurrence and metastasis across the board and prolonging disease-free survival, and the protective effect of anastrozole persists even after 4 years of a standardized course of treatment.
What’s the application of Anastrozole?
Anastrozole is a chemical substance, third-generation aromatase inhibitor. It is used to treat postmenopausal patients with advanced breast cancer. UsesCure breast cancer. UsesThird-generation aromatase inhibitor. Used for the treatment of postmenopausal patients with advanced breast cancer. A potent and selective triazole aromatase inhibitor that inhibits cytochrome P-450-dependent aromatase and thereby blocks the biosynthesis of estrogen, the main stimulus for breast cancer cell growth. Treatment of advanced breast cancer, especially in postmenopausal women who have recurred after adjuvant treatment with hormones.
Conclusion
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