Amphotericin B CAS# 1397-89-3

SOLUBLE, Promotion Season Now in Store and Free Sample for Testing with Factory Price

• Chemical Name:  Amphotericin B
• CAS No.:     1397-89-3
• Molecular Fomula: ：C47H73NO17
• Molecular weight：924.08
• Appearance: yellow powder
• Sample：Available

Send Inquiry


Download Quotation

Description of SOLUBLE

• Amphotericin B is an antifungal drug often used intravenously for serious systemic fungal infections and is the only effective treatment for some fungal infections.
  Common side effects include a reaction of fever, shaking chills, headaches and low blood pressure soon after it is infused, as well as kidney and electrolyte problems. Allergic symptoms including anaphylaxis may occur.
  It was originally extracted from Streptomyces nodosus, a filamentous bacterium, in 1955, at the Squibb Institute for Medical Research. Its name originates from the chemical’s amphoteric properties. It is on the World Health Organization’s List of Essential Medicines, the most important medications needed in a basic health system.
  It is of the polyene class. Currently, the drug is available in many forms. Either “conventionally” complexed with sodium deoxycholate (ABD), as a cholesteryl sulfate complex (ABCD), as a lipid complex (ABLC), and as a liposomal formulation (LAMB). The latter formulations have been developed to improve tolerability and decrease toxicity, but may show considerably different pharmacokinetic characteristics compared to conventional amphotericin B

Basic Info of SOLUBLE

Basic Info
Numbering system
Properties
Safety Info
Basic Info

Numbering system

Properties

Safety Info

What is Amphotericin B?

• With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives. One such product is Amphotericin B   which has developed particularly rapidly in recent years. Do you know about Amphotericin B?
• The official answer：Light yellow to orange-yellow needle-like crystals or powder. Insoluble in water, ethanol, soluble in acidic DMF, DMSO, slightly soluble in DMF, acidic or alkaline aqueous low-grade alcohol. Odorless, almost tasteless. Easily destroyed by light, heat, and acid. Using Streptomyces nodosus strain as strain, deep fermentation by aeration in liquid medium containing carbohydrates and organic nitrogen sources, and amphotericin is extracted from the fermentation broth when considerable potency units are reached. Amphotericin contains A and B components, A component is less toxic, weak antifungal effect, not used clinically, B component is strong, called amphotericin B.

What’s the application of Amphotericin B?

• It has a powerful inhibitory effect or killing effect on many kinds of fungal infections, such as Cryptococcus neoformans, Candida albicans, Histoplasma capsulatum, Dermatophytes, Schenck’s spore filamentous fungi, Trichoderma spp., and Coccidioides Crassus. It is mainly used as the drug of choice for deep fungal diseases. For antifungal use Polyene antifungal drug. It binds to sterols on the fungal cell membrane, impairs the permeability of the membrane, causes leakage of potassium ions, nucleotides, and amino acids from the fungal cell and disrupts the normal metabolism, and acts as an inhibitor.

Conclusion

Sincere to the customer and in good faith of quality is our forever followed motto. It’s the basement to be a human and do business. We take all responsibility for our products and service sincerely. We are a company integrating R&D, production, and sales. The design, research, and development of pharmaceutical intermediates including more than 330 kinds of pharmaceutical intermediates such as Anti-infectives, Cardiovascular and Cerebrovascular Systems, Digestive System, Santi-tumor, Nervous System, Geriatric Drugs, and Gynecological Drugs. At the same time, we have more than 4,000 factories in strategic cooperation with nearly 50,000 chemical products, so we can provide you with a one-stop purchasing service, which greatly saves customers’ procurement costs and time.

Keywords of Amphotericin B

SOLUBLE , 1397-89-3, buy  SOLUBLE, Amphotericin B  supplier, purchase  SOLUBLE,  SOLUBLE cost,  SOLUBLE manufacturer, order  SOLUBLE, high pur SOLUBLE  SOLUBLE

Hot Products