4,7-Dichloroquinoline acid Promotion Season Now in Store and Free Sample for Testing with Factory Price
- Chemical Name: 4,7-Dichloroquinoline acid
- CAS No.: 86-98-6
- Molecular Fomula: ： C9H5Cl2N
- Molecular weight： 198.05
- Appearance: White powder
- Sample：Available
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Description of Amobiquine Impurity 1
4,7-Dichloroquinoline is used in the synthesis of hybrid aminoquinoline-triazine derivatives that show anti-microbial activity. In addition, it is used in the synthesis of novel oxazolidinones as anti-microbial agents showing efficacy against common bacterial strains. Chloroquinoline impurity.
Basic Info of Amobiquine Impurity 1
Basic Info
Numbering system
Properties
Safety Info
Basic Info
| Chemical Name | Amobiquine Impurity 1 |
| Synonyms | Quinoline, 4,7-dichloro-;4,7-DICHLORCHINOLIN;4,7-DICHLOROQUINOLINE FOR SYNTHESIS;4,7-Dichloroquinoline,tech.;4,7-DICHLOLROQUINOLINE;Expand |
| CAS No. | 86-98-6 |
| Molecular Formula | C9H5Cl2N |
| Molecular Weight | 198.04900 |
| PSA | 12.89000 |
| LogP | 3.54160 |
Numbering system
| EINECS number | 201-714-7 |
| MDL number | MFCD00006774 |
Properties
| Appearance & Physical State | yellow to brown crystals |
| Density | 1.407 g/cm3 |
| Boiling Point | 148ºC |
| Melting Point | 84-86ºC |
| Flash Point | 164ºC |
| Refractive Index | 1.66 |
| Water Solubility | insoluble |
| Stability | Stable at room temperature in closed containers under normal storage and handling conditions. |
| Storage Condition | Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. |
Safety Info
| RTECS | VB4200000 |
| Safety Statements | S22-S26-S36 |
| HS Code | 2933499013 |
| WGK Germany | 3 |
| Risk Statements | R36/37/38 |
| Hazard Codes | Xi |
| Caution Statement | P261; P305 + P351 + P338 |
| Symbol | GHS07 |
| Signal Word | Warning |
| Hazard Declaration | H315; H319; H335 |
What is Amobiquine Impurity 1?
- With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives. One such product is 4,7-Dichloroquinoline which has developed particularly rapidly in recent years. Do you know about 4,7-Dichloroquinoline ?
- The official answer：4,7-Dichloroquinoline is a chemical substance with the molecular formula C9H5Cl2N. 4,7-Dichloroquinoline is an important intermediate of the antimalarial drug chloroquine phosphate, usually obtained by chlorination and isolation of 7-chloro-4-hydroxyquinoline. Molecular weight is 198.05. melting point 81-83°C(lit.) boiling point 298.4°F(148°C) density 1.4178(rough estimate) refractive index 1.6300(estimate) flash point 164°C storage conditions 2-30°C solubility chloroform:soluble50mg/mL, clear,colorless to greenish-mellow acidity coefficient(pKa)1.99±0.27(Predicted)
What’s the application of Amobiquine Impurity 1?
4,7-Dichloroquinoline is used for the synthesis of heteroaminoquinoline-triazine derivatives with antimicrobial activity. In addition, it is used for the synthesis of novel oxazolidinones as antimicrobial agents that show effective efficacy against common bacterial strains. Chloroquinoline impurity. Uses Used as intermediate of drug chloroquine phosphate 4,7-dichloroquinoline is an important intermediate of anti-malarial drug chloroquine phosphate, hydroxychloroquine sulfate, amodiaquine, and other drugs, usually obtained from 7-chloro-4-hydroxyquinoline after chlorination and isolation
Conclusion
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