4-Dimethylaminopyridine , Promotion Season Now in Store and Free Sample for Testing with Factory Price
- Chemical Name: 4-Dimethylaminopyridine
- CAS No.: 1122-58-3
- Molecular Fomula:C7H10N2
- Molecular weight:122.17
- Appearance: White powder
- Sample: Available
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Description of 4-Dimethylaminopyridine CAS# 1122-58-3
4-Dimethylaminopyridine (DMAP) is a derivative of pyridine with the chemical formula (CH3)2NC5H4N. This colourless solid is of interest because it is more basic than pyridine, owing to the resonance stabilisation from the NMe2 substituent.
Because of its basicity, DMAP is a useful nucleophilic catalyst for a variety of reactions such as esterifications with anhydrides, the Baylis-Hillman reaction, hydrosilylations, tritylation, the Steglich rearrangement, Staudinger synthesis of β-lactams and many more. Chiral DMAP analogues are used in kinetic resolution experiments of mainly secondary alcohols and Evans auxiliary type amides.
Basic Info of 4-Dimethylaminopyridine CAS# 1122-58-3
Basic Info
Numbering system
Properties
Safety Info
Basic Info
Chemical Name | 4-Dimethylaminopyridine |
Synonyms | 4-Dimethylaminopyrid;AURORA KA-6495;N-(4-Pyridyl)dimethylamine;4-Pyridinamine, N,N-dimethyl-;4-Dimethylaminepyridine;Expand |
CAS No. | 1122-58-3 |
Molecular Formula | C7H10N2 |
Molecular Weight | 122.16800 |
PSA | 16.13000 |
LogP | 1.14760 |
Numbering system
EINECS number | 214-353-5 |
MDL number | MFCD00006418 |
BRN number | 110354 |
RTECS number | US9230000 |
Properties
Appearance & Physical State | white to yellow crystalline powder |
Density | 1.012 g/cm3 |
Boiling Point | 162ºC (50 mmHg) |
Melting Point | 108-113ºC |
Flash Point | 110ºC |
Refractive Index | n20/D 1.431 |
Water Solubility | 76 g/L (25 ºC) |
Stability | Stable. Incompatible with acids, oxidizing agents. |
Storage Condition | Store in dark |
Vapor Pressure | 0.431mmHg at 25°C |
Safety Info
RTECS | US8400000 |
Hazard Class | 8 |
Safety Statements | S26-S28-S36/37/39-S45 |
HS Code | 2933399090 |
Packing Group | II |
WGK Germany | 3 |
RIDADR | UN 1760/2811 |
Risk Statements | R24/25; R34 |
Hazard Codes | T |
Caution Statement | P280; P301 + P312 + P330; P302 + P352 + P312; P304 + P340 + P312; P305 + P351 + P338; P337 + P313 |
Symbol | GHS06, GHS08 |
Hazard Declaration | H302; H311; H315; H319; H335; H351 |
Signal Word | Danger |
What is 4-Dimethylaminopyridine CAS# 1122-58-3?
With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives. One such product is it which has developed particularly rapidly in recent years. Do you know about it?
The official answer:4-Dimethylaminopyridine is a new type of efficient catalyst widely used in chemical synthesis, white crystalline powder with molecular formula C7H10N2.
What’s the application of 4-Dimethylaminopyridine CAS# 1122-58-3?
4-Dimethylaminopyridine is a new type of highly efficient catalyst widely used in chemical synthesis in recent years. 4-Dimethylaminopyridine is a new type of highly efficient catalyst widely used in chemical synthesis in recent years. 4-Dimethylaminopyridine is a new type of highly efficient catalyst widely used in chemical synthesis in recent years. 4-Dimethylaminopyridine is a new type of highly efficient catalyst widely used in chemical synthesis in recent years. 4-Dimethylaminopyridine is a new type of highly efficient catalyst widely used in chemical synthesis in recent years. 4-Dimethylaminopyridine is a new type of highly efficient catalyst widely used in chemical synthesis in recent years. Chemical book acylation (phosphorylation, sulfonylation, carbonylation) of high potential resistance, low reactivity alcohols, and amines, with an activity about 104-6 times that of pyridine. It has a high catalytic capacity for acylation, alkylation, etherification, esterification, and ester exchange in organic synthesis, drug synthesis, pesticides, pharmaceuticals, dyes, fragrances, polymer chemistry, and analytical chemistry, and is extremely effective in improving yields.
Conclusion
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