About Milbemycin Oxime
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8 9 月, 2021About Milbemycin Oxime
What is milbemycin oxime?
Milbemycin oxime (trade name Interceptor) is a medicine to prevent heartworm disease and treat internal parasites (such as hookworms and roundworms) in dogs and cats.
Milbemycin oxime (trade name Interceptor) is a medicine to prevent heartworm disease and treat internal parasites (such as hookworms and roundworms) in dogs and cats.
It is also found in combination products (such as Sentinel, Sentinel Spectrum, and Trifexis) with other drugs (lufenuron or spinosyn). In addition to treating internal parasites and preventing heartworms, these combination products are also flea preventives.
Milbemycin is also used "off-label" or "off-label" to treat mite infections in dogs. Many drugs are usually prescribed for off-label use in veterinary medicine. In these cases, follow the veterinarian's instructions and warnings very carefully.
Milbemycin is also used "off-label" or "off-label" to treat mite infections in dogs. Many drugs are usually prescribed for off-label use in veterinary medicine. In these cases, follow the veterinarian's instructions and warnings very carefully.
How is milbemycin oxime administered?
Milbemycin is administered orally together with flavored oral tablets. It can be given with or without food, but if your pet experiences discomfort or vomiting after taking milbemycin on an empty stomach, try giving a small amount of food.
The drug should take effect within 1 to 2 days for internal parasites and within 24 hours for external parasites, and the clinical symptoms should be improved accordingly.
Milbemycin is administered orally together with flavored oral tablets. It can be given with or without food, but if your pet experiences discomfort or vomiting after taking milbemycin on an empty stomach, try giving a small amount of food.
The drug should take effect within 1 to 2 days for internal parasites and within 24 hours for external parasites, and the clinical symptoms should be improved accordingly.
What if I miss giving my pet medicine (or my delivery is late)?
Give the missed dose as soon as you remember it, and then wait for the dose interval recommended by your veterinarian before giving the next dose. Don't give your dog two doses at a time, or more.
If you are using milbemycin as a heartworm preventive and have not taken this medication for more than 8 weeks, please contact your veterinarian for guidance.
Give the missed dose as soon as you remember it, and then wait for the dose interval recommended by your veterinarian before giving the next dose. Don't give your dog two doses at a time, or more.
If you are using milbemycin as a heartworm preventive and have not taken this medication for more than 8 weeks, please contact your veterinarian for guidance.
Are there any potential side effects?
Milbemycin is well tolerated at regular doses. When used in higher doses to treat mites, side effects have been observed. If you observe any of the following conditions, please contact your veterinarian immediately:
Depression, lack of energy, or weakness
Trip or crash
Seizures or coma
Dilated (large) pupil
Excessive drooling
Certain breeds, such as sheepdogs, sheepdogs and sheepdogs or sheepdog hybrids, are only sensitive to moderate doses of milbemycin and may have side effects at lower doses.
This medium-acting drug should stop working within a few days, but the effect on pets with liver or kidney disease may be longer.
Milbemycin is well tolerated at regular doses. When used in higher doses to treat mites, side effects have been observed. If you observe any of the following conditions, please contact your veterinarian immediately:
Depression, lack of energy, or weakness
Trip or crash
Seizures or coma
Dilated (large) pupil
Excessive drooling
Certain breeds, such as sheepdogs, sheepdogs and sheepdogs or sheepdog hybrids, are only sensitive to moderate doses of milbemycin and may have side effects at lower doses.
This medium-acting drug should stop working within a few days, but the effect on pets with liver or kidney disease may be longer.
Are there any risk factors for this drug?
Milbemycin is safe for most pets. Milbemycin should not be used for:
Dogs that do not currently test negative for heartworm
Puppies less than 4 weeks old or puppies or dogs weighing less than 2 pounds (900 grams)
Cats younger than 6 weeks of age or cats or kittens weighing less than 1.5 pounds (680 grams)
Certain breeds of dogs (such as sheepdogs, sheepdogs and sheepdogs or sheepdog hybrids) are more sensitive to milbemycin than other breeds. This is usually due to a specific genetic mutation (MDR1) that makes them unable to tolerate high doses of milbemycin. The dose used to prevent heartworms can be safely used in dogs of these breeds.
Your veterinarian will advise you on the safety of using milbemycin in your dog.
Milbemycin is safe for most pets. Milbemycin should not be used for:
Dogs that do not currently test negative for heartworm
Puppies less than 4 weeks old or puppies or dogs weighing less than 2 pounds (900 grams)
Cats younger than 6 weeks of age or cats or kittens weighing less than 1.5 pounds (680 grams)
Certain breeds of dogs (such as sheepdogs, sheepdogs and sheepdogs or sheepdog hybrids) are more sensitive to milbemycin than other breeds. This is usually due to a specific genetic mutation (MDR1) that makes them unable to tolerate high doses of milbemycin. The dose used to prevent heartworms can be safely used in dogs of these breeds.
Your veterinarian will advise you on the safety of using milbemycin in your dog.
Are there any drug interactions that I should be aware of?
Other drugs can interact with milbemycin (for example, cyclosporine, amidarone, diltiazem, azole antifungals, erythromycin). Be sure to tell your veterinarian of any medications your pet is taking (including vitamins, supplements, or herbal remedies).
Is there any need to monitor this drug?
Before accepting any products containing milbemycin, your pet should be tested for heartworm. If your pet has a large number of immature worms and is given milbemycin, a life-threatening reaction may occur.
Dogs with potential milbemycin sensitivity can be screened before receiving the drug. DNA testing can determine whether a pet has a genetic mutation that causes an adverse reaction to milbemycin.
Other drugs can interact with milbemycin (for example, cyclosporine, amidarone, diltiazem, azole antifungals, erythromycin). Be sure to tell your veterinarian of any medications your pet is taking (including vitamins, supplements, or herbal remedies).
Is there any need to monitor this drug?
Before accepting any products containing milbemycin, your pet should be tested for heartworm. If your pet has a large number of immature worms and is given milbemycin, a life-threatening reaction may occur.
Dogs with potential milbemycin sensitivity can be screened before receiving the drug. DNA testing can determine whether a pet has a genetic mutation that causes an adverse reaction to milbemycin.
How do I store milbemycin?
Store milbemycin oxime products in a cool and dry place at room temperature, away from heat and direct sunlight. Do not store this medicine in the bathroom, near the kitchen sink, or in a humid place. Exposure to high temperature or humidity may reduce the effectiveness of the medicine.
What should I do in an emergency?
If you suspect an overdose or an adverse reaction, please call your veterinarian's office immediately. If they are not available, follow their instructions to contact emergency facilities.
Store milbemycin oxime products in a cool and dry place at room temperature, away from heat and direct sunlight. Do not store this medicine in the bathroom, near the kitchen sink, or in a humid place. Exposure to high temperature or humidity may reduce the effectiveness of the medicine.
What should I do in an emergency?
If you suspect an overdose or an adverse reaction, please call your veterinarian's office immediately. If they are not available, follow their instructions to contact emergency facilities.