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- Chemical Name: Tetradecylthioacetic acid
- CAS No.: 2921-20-2
- Molecular Fomula: ：C16H32O2S
- Molecular weight：288.49
- Appearance:White powder
- Sample：Available
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Description of 1-MONO,
- Tetradecylthioacetic acid (TTA) is a synthetic fatty acid used as a nutritional supplement.
TTA acts as a peroxisome proliferator-activated receptor alpha (PPARα) agonist and increases mitochondrial fatty acid oxidation in vitro. In rodent studies, TTA has been reported to have other activities such as reducing inflammation and preventing high fat diet induced adiposity and insulin resistance.
In human clinical study, there have been mixed observations in preliminary studies. One Phase I study showed no significant changes in the blood lipids or free fatty acids and another showed that TTA attenuates dyslipidemia in patients with type 2 diabetes mellitus.
Basic Info of 1-MONO,
Basic Info
Numbering system
Properties
Safety Info
Basic Info
| Chemical Name | Tetradecylthioacetic Acid |
| Synonyms | Tetradecylthioacetic acid; |
| CAS No. | 2921-20-2 |
| Molecular Formula | C16H32O2S |
| Molecular Weight | 288.48900 |
| PSA | 62.60000 |
| LogP | 5.50530 |
Numbering system
| UNII | 7ZU5I25S2O |
Properties
| Appearance & Physical State | white |
| Density | 0.957 g/cm3 |
| Boiling Point | 402.6ºC at 760 mmHg |
| Melting Point | 65-73ºC |
| Flash Point | 197.3ºC |
| Refractive Index | 1.481 |
| Storage Condition | -20ºC Freezer |
| Vapor Pressure | 1.32E-07mmHg at 25°C |
Safety Info
| HS Code | 2930909090 |
| WGK Germany | 3 |
What is Tetradecylthioacetic acid?
- With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives. One such product is Tetradecylthioacetic acid which has developed particularly rapidly in recent years. Do you know about Tetradecylthioacetic acid?
- The official answer：Tetradecylthioacetic acid is a chemical substance with a melting point of 65-73°C and a boiling point of 402.6±28.0 °C (Predicted)Density 0.957±0.06 g/cm3 (Predicted)RTECS No. AJ5087000。
What’s the application of Tetradecylthioacetic acid?
- TTAisanovelthio-fattyacidwhichcannotundergobeta-oxidation.ItinducesapoptosisinIPC-81leukemiacellsviadepolarizationofmitochondrialmembranepotentialandinhibitsChemicalbookgliomacellproliferation.TTAcompletelypreventshighfatdiet-inducedinsulinresistanceandadiposityinWistarrats.ActivatesrodentPPARwithrankorderPPARα>PPARδ>PPARγ.
Conclusion
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