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- Chemical Name: Tazarotene
- CAS No.: 118292-40-3
- Molecular Fomula: :C21H21NO2S
- Molecular weight:351.46
- Appearance:White powder
- Sample:Available
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Description of Tazorac
Tazarotene (marketed as Tazorac, Avage, Zorac, and Fabior) is a third-generation prescription topical retinoid sold as a cream, gel, or foam. Tazarotene is a member of the acetylenic class of retinoids. This medication is approved for treatment of psoriasis, acne, and sun damaged skin (photodamage). It is commonly sold in two concentrations: 0.05% and 0.1%.
Basic Info of Tazorac
Basic Info
Numbering system
Properties
Safety Info
Basic Info
Chemical Name | tazarotene |
Synonyms | Tazarotene;ethyl 6-[2-(4,4-dimethyl-2,3-dihydrothiochromen-6-yl)ethynyl]pyridine-3-carboxylate;Ethyl 6-((4,4-dimethylthiochroman-6-yl)ethynyl)nicotinate; |
CAS No. | 118292-40-3 |
Molecular Formula | C21H21NO2S |
Molecular Weight | 351.46200 |
PSA | 64.49000 |
LogP | 4.43150 |
Numbering system
MDL number | MFCD00867628 |
Properties
Appearance & Physical State | White Solid |
Density | 1.22 g/cm3 |
Boiling Point | 499.8ºC at 760 mmHg |
Melting Point | 97-98ºC |
Flash Point | 256.1ºC |
Refractive Index | 1.624 |
Vapor Pressure | 4.03E-10mmHg at 25°C |
Safety Info
HS Code | 2942000000 |
What is Tazarotene?
- With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives. One such product is Tazarotene which has developed particularly rapidly in recent years. Do you know about Tazarotene ?
- The official answer:Tazarotene is the first receptor-selective, third-generation aromatic retinoid that selectively binds mainly to two retinoic acid receptors (RAR-β; RAR-γ), but not to retinoic acid X receptor (RXR). It is clinically safe and effective for the treatment of psoriasis and acne, and is used in keratosis pilaris, follicular sebaceous gland disease, and pre-cancerous skin lesions, with promising clinical development applications.
What’s the application of Tazarotene?
- Tazarotene is a third-generation retinoid dermatological drug, a vitamin A-like precursor for topical use in the skin, with effects such as regulating epidermal cell differentiation and proliferation and is mainly indicated for the treatment of plaque psoriasis Vulgaris. Tazarotene cream can also be used for the treatment of facial acne. It contains 15mg/30g of the active ingredient and is applied topically as a gel, with an appropriate amount applied to the affected area half an hour before bedtime each night. Before application, wash the affected area first, wait for the skin to dry, and then apply the drug evenly on the lesions to form a thin film; after application, the drug should be rubbed gently to promote the absorption of the drug. A pea-sized gel can cover a large area of skin lesions on the palm, and the area of application should not exceed 20% of the body surface area. Wash your hands with soap after rubbing the medication. Psoriasis is a common benign, acute, or chronic inflammatory skin disease. It occurs based on a genetic predisposition. Trauma or irritation of normal skin can trigger the appearance of psoriatic lesions (Koebner phenomenon): psoriasis has several different manifestations – the most common is the plaque type. The eruptive (punctate) form of psoriasis consists of numerous lesions of 3 to 10 mm. Occasionally it occurs following stress or strep throat. In severe cases, life-threatening forms such as pustular and erythrodermic psoriasis may occasionally occur. Sudden onset of plaque or generalized erythrodermic psoriasis may be associated with HIV infection.
Conclusion
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