Tamoxifen CAS# 10540-29-1

Tamoxifen, Promotion Season Now in Store and Free Sample for Testing with Factory Price

• Chemical Name: Tamoxifen
  CAS No.: 10540-29-1
  Molecular Fomula: C26H29NO
  Molecular weight: 371.51
  Appearance: Crystals from pet ether neat
  Sample: Available

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Description of Genox

Genoxis a selective estrogen response modifier (SERM), protein kinase C inhibitor and anti-angiogenetic factor. Genoxis a prodrug that is metabolized to active metabolites 4-hydroxytamoxifen (4-OHT) and endoxifen by cytochrome P450 isoforms CYP2D6 and CYP3A4. In breast cancer, the gene repressor activity of Genoxagainst ERBB2 is dependent upon PAX2. Blocks estradiol-stimulated VEGF production in breast tumor cells. Protein kinase C inhibitor. Induces apoptosis in human malignant glioma cell lines. Tamoxifen and its metabolite 4-hydroxytamoxifen are selective estrogen response modifiers (SERMs) that act as estrogen antagonists in mammary gland. Blocks estradiol-stimulated VEGF production in breast tumor cells.

Basic Info of Tamoxifen

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Basic Info

Numbering system

Properties

Safety Info

What is Genox?

• With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives. One such product is Genoxwhich has developed particularly rapidly in recent years. Do you know about Tamoxifen?
• The official answer: Genox, chemically known as (Z)-2-[4-(1,2-diphenyl-1-butene)phenoxy]-N, N-dimethylethanolamine, is an organic compound with the molecular formula C26H29NO, clinically used for the treatment of advanced breast and ovarian cancers.
• In clinical treatment of breast cancer, the efficiency is generally in the 30% role, with better efficacy in estrogen receptor-positive patients (49%) and poor efficacy in negative patients (7%). Both premenopausal and postmenopausal patients can be used, while postmenopausal and those over 60 years old have better results than premenopausal and younger patients.

What’s the application of Genox?

It is used for advanced cachectic cancer and is also effective for ovarian cancer, and is more effective when combined with other anti-cancer drugs. Used for the treatment of advanced breast cancer, also effective for ovarian cancer, better in combination with other anti-cancer drugs

Conclusion

Sincere to the customer and in good faith of quality is our forever followed motto. It’s the basement to be a human and do business. We take all responsibility for our products and service sincerely. We are a company integrating R&D, production, and sales. The design, research, and development of pharmaceutical intermediates including more than 330 kinds of pharmaceutical intermediates such as Anti-infectives, Cardiovascular and Cerebrovascular Systems, Digestive System, Santi-tumor, Nervous System, Geriatric Drugs, and Gynecological Drugs. At the same time, we have more than 4,000 factories in strategic cooperation with nearly 50,000 chemical products, so we can provide you with a one-stop purchasing service, which greatly saves customers’ procurement costs and time.

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