Pyridine CAS# 110-86-1

azabenzene, Promotion Season Now in Store and Free Sample for Testing with Factory Price

• Chemical Name:  Pyridine
• CAS No.:     110-86-1
• Molecular Fomula: ： C5H5N
• Molecular weight：79.1
• Appearance:colorless liquid
• Sample：Available

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Basic Info of azabenzene

Basic Info
Numbering system
Properties
Safety Info
Basic Info

Numbering system

Properties

Safety Info

What is Pyridine ?

• With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives. One such product is azabenzene   which has developed particularly rapidly in recent years. Do you know about azabenzene?
• The official answer：azabenzene (molecular formula C6H5N) contains a nitrogen heterocyclic compound, that is, a -CH = in the benzene molecule is replaced by nitrogen compounds, similar to benzene, with the same electronic structure, still aromatic, so also known as nitrogen benzene and nitrogen benzene, at room temperature is a colorless liquid with a special smell, melting point -41.6 ℃, boiling point 115.2 ℃, and water to form an azeotropic mixture. Boiling point 92-93℃. （It is easily soluble in water, ethanol, ether, and most other organic solvents, and can be used as a solvent itself. azabenzene was firstly isolated from bone tar, then it was found that coal tar, gas, shale oil, and petroleum also contain azabenzene and its congeners, such as 2-methylazabenzene and 2,6-dimethylazabenzene. azabenzene and its derivatives are more stable than benzene, and their reactivity is similar to that of nitrobenzene. Due to the electron-absorbing effect of nitrogen atoms in the ring, the electron density at the 2,4,6 positions is lower than that at the 3,5 positions, and typical aromatic electrophilic substitution reactions occur at the 3,5 positions, but the reactivity is lower than that of benzene, and nitration, halogenation and sulfonation reactions are generally not easy to occur. In addition, these substitution reactions are carried out in acidic media, and azabenzene forms positively charged ions, making the electrophilic reagents less accessible. 2- or 4-halogenated azabenzene halogens are active. Due to the low electron density at the 2 and 6 positions, nucleophilic substitution reactions can occur at this position, such as with sodium amide or potassium hydroxide, to give the corresponding 2-aminoazabenzene or 2-hydroxy azabenzene.

What’s the application of Pyridine ?

• Among the many derivatives of azabenzene, some are important drugs and some are important components of vitamins or enzymes. For example, the amide of azabenzene-3-carboxylic acid (i.e. nicotinamide), forms an important dinucleotide with adenine (see purine), ribose and phosphate in coenzyme I. Isoniazid, a derivative of azabenzene, is an oral antituberculosis drug. Isoniazid, a derivative of azabenzene, is an oral antituberculosis drug. 2-Methyl-5-vinyl azabenzene is an important raw material for the synthesis of rubber. azabenzene can be obtained from natural coal tar, or acetaldehyde and ammonia. In addition to being a solvent, azabenzene is also used industrially as a denaturant, dyeing aid, and a starting material for the synthesis of a range of products, including pharmaceuticals, disinfectants, dyes, food flavorings, adhesives, explosives, etc. Information on downstream products with related uses: Agrochemicals: Herbicides (paraquat, diquat, picloram): for field weed control, aquatic weed control, Insecticides (chlorpyrifos, chlorpyrifos-methyl, pyrethroids): broad-spectrum insecticides, high-efficiency, low-toxicity household hygiene insecticides Pyrithione salts: zinc pyrithione or 2-mercaptopurine-N-oxide zinc salts, sodium pyrithione (use: broad-spectrum antimicrobial agent, can kill Gram (negative, positive) bacteria, fungi, is the international common anti-dandruff shampoo active agent; zinc pyrithione can be mixed into carpet adhesive to inhibit bacterial growth; sodium pyrithione can be mixed into metal processing fluid antifungal growth) Synthetic quaternary salts: cetyl pyridinium chloride (production of mouthwash, hair care products regulator, phase transfer catalyst) new polymer compounds: poly-4-(3-pyrrolidinyl) azabenzene (with efficient acylation catalyst group) piperidine: piperidinyl Bochum tetrasulfide (rubber hardening accelerator), N,N-dimethylpiperidinium salt chloride (plant growth regulator), epoxy curing agent, group protector, and Special solvents.

Conclusion

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