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- Chemical Name: Povidone iodine
- CAS No.: 25655-41-8
- Molecular Fomula:C6H9I2NO
- Molecular weight:364.95
- Appearance: Red amorphous powder
- Sample:Available
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Description of disphex
Povidone-iodine (PVP-I), brand name Wokadine, Pyodine, and Betadine is a stable chemical complex of polyvinylpyrrolidone (povidone, PVP) and elemental iodine. It contains from 9.0% to 12.0% available iodine, calculated on a dry basis.
This unique complex was discovered in 1955 at the Industrial Toxicology Laboratories in Philadelphia by H. A. Shelanski and M. V. Shelanski. They carried out tests in vitro to demonstrate anti-bacterial activity, and found that the complex was less toxic in mice than tincture of iodine.
Human clinical trials showed the product to be superior to other iodine formulations.
Betadine was immediately marketed, and has since become the universally preferred iodine antiseptic.
It is on the WHO Model List of Essential Medicines, the most important products needed in a basic health system.
Basic Info of disphex
Basic Info
Numbering system
Properties
Safety Info
Basic Info
Chemical Name | Povidone iodine |
Synonyms | Isobetadyne;Povidone-iodine;Disphex;1-ethenylpyrrolidin-2-one,molecular iodine;Polyvinylpyrrolidone-Iodine Complex;Expand |
CAS No. | 25655-41-8 |
Molecular Formula | C6H9I2NO |
Molecular Weight | 364.95100 |
PSA | 20.31000 |
LogP | 2.46160 |
Numbering system
MDL number | MFCD00084483 |
PubChem number | 24899316 |
RTECS number | TR1579600 |
Properties
Appearance & Physical State | A red-brown crystalline powder |
Boiling Point | 217.6ºC at 760 mmHg |
Melting Point | 300ºC |
Flash Point | 93.9ºC |
Stability | Stable under normal temperatures and pressures. |
Storage Condition | Keep container closed when not in use. Store in a cool, dry, well-ventilated area away from incompatible substances. Store in air tight containers. |
Vapor Pressure | 0.132mmHg at 25°C |
Safety Info
Safety Statements | S24/25 |
HS Code | 3808940010 |
What is Povidone iodine?
- With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives. One such product isPovidone iodine which has developed particularly rapidly in recent years. Do you know aboutPovidone iodine ?
- The official answer:Povidone-iodine is a loose complex made by combining elemental iodine and polymeric carrier, with povidone acting as a carrier and solubilizer. It is yellowish-brown to brownish red amorphous powder at room temperature. It is slightly odorous, easily soluble in water or ethanol, acidic in aqueous solution, insoluble in ether, chloroform, acetone, methane, and carbon tetrachloride. The povidone-iodine aqueous solution has no disadvantages of tincture of iodine, shallow coloring, easy elution, little irritation to a mucous membrane, no ethanol deiodination, no corrosive effect, and low toxicity.
What’s the application of Povidone iodine?
- It has the bactericidal effect of iodine and is used as a bactericidal disinfectant and bacteriostatic agent in pharmaceuticals, antiseptic for eye drops, nasal drops, creams, etc. It can also be made into disinfectant solution mainly used in hospitals for skin disinfection and equipment disinfection such as surgery and injection, as well as prevention of infection in the oral cavity, gynecology, surgery, dermatology, etc.; household utensils and appliances disinfection; food industry, breeding industry for disinfection and animal disease prevention and control, etc. It is international It is the preferred iodine carrier for medical sterilants and sanitary disinfectants containing iodine in China. Tamed iodine”, this product can gradually release iodine and play antibacterial effect, its mechanism of action is to make the bacterium protein denaturation, death. It is effective against bacteria, fungi, and viruses, and is characterized by low irritation to tissues.
Conclusion
Sincere to the customer and in good faith of quality is our forever followed motto. It’s the basement to be a human and do business. We take all responsibility for our products and service sincerely. We are a company integrating R&D, production, and sales. The design, research, and development of pharmaceutical intermediates including more than 330 kinds of pharmaceutical intermediates such as Anti-infectives, Cardiovascular and Cerebrovascular Systems, Digestive System, Santi-tumor, Nervous System, Geriatric Drugs, and Gynecological Drugs. At the same time, we have more than 4,000 factories in strategic cooperation with nearly 50,000 chemical products, so we can provide you with a one-stop purchasing service, which greatly saves customers’ procurement costs and time.
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