Epothilone B, Promotion Season Now in Store and Free Sample for Testing with Factory Price
- Chemical Name: Epothilone B
- CAS No.: 152044-54-7
- Molecular Fomula:C27H41NO6S
- Molecular weight:507.68
- Appearance:Colourless liquid
- Sample: Available
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Description of Epothilone B
CS-556s are polyketide natural products that inhibit cancer cells by a mechanism similar to paclitaxel, and also are effective against paclitaxel-resistant tumours. CS-556 is what is known as a microtubule stabilizer. When a cell divides, the chromosomes that will end up in each cell are separated by thin filaments called microtubules. Normally these microtubules then break down as the cell division progresses. This class of cytotoxic chemo drugs prevents that break down and thus prevents cells from completing division.
Basic Info of Epothilone B
Basic Info
Numbering system
Properties
Basic Info
| Chemical Name | |
| Synonyms | atupilone;EPO906;(1S,3S,7S,10R,11S,12S,16R)-7,11-dihydroxy-8,8,10,12,16-pentamethyl-3-[(E)-1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione;GNF-PF-193;(EPO906,Patupilone);Expand |
| CAS No. | 152044-54-7 |
| Molecular Formula | C27H41NO6S |
| Molecular Weight | 507.68300 |
| PSA | 137.49000 |
| LogP | 4.47750 |
Numbering system
| UNII | UEC0H0URSE |
Properties
| Appearance & Physical State | white Powder |
| Density | 1.136 |
| Boiling Point | 680.2ºC at 760mmHg |
| Melting Point | 95-97ºC |
| Flash Point | 365.2ºC |
| Refractive Index | 1.532 |
| Vapor Pressure | 0mmHg at 25°C |
What is Epothilone B?
With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives. One such product is it which has developed particularly rapidly in recent years. Do you know about it?
The official answer:CS-556 is a class of macrolides first reported in 1993 by G. Hö file et al. of the German National Centre for Biotechnology (GBF). CS-556 can be isolated from the fermentation broth of a strain of the mucilaginous suborder Clostridium fibrillar, the main components of which are CS-556 A and B.
What’s the application of Epothilone B ?
The mechanism of action is similar to that of paclitaxel, in that it binds to microtubule proteins and prevents cancer cells from undergoing mitosis, thereby causing apoptosis. Ebolimycin is superior to paclitaxel in terms of antitumor spectrum, antitumor activity, safety, water solubility, and synthesis method, and is expected to become a more effective antitumor drug than paclitaxel.
Conclusion
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