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- Chemical Name: Cephalexin
- CAS No.: 15686-71-2
- Molecular Fomula: : C16H17N3O4S
- Molecular weight:347.39
- Appearance:White crystalline powder
- Sample:Available
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Description of cefa-iskia
Cefalexin, also spelled cephalexin, is an antibiotic that can treat a number of bacterial infections. It kills gram-positive and some gram-negative bacteria by disrupting the growth of the bacterial cell wall. Cefalexin is a beta-lactam antibiotic within the class of first-generation cephalosporins. It works similarly to other agents within this class, including intravenous cefazolin, but can be taken by mouth.
Cefalexin can treat certain bacterial infections, including those of the middle ear, bone and joint, skin, and urinary tract. It may also be used for certain types of pneumonia, strep throat, and to prevent bacterial endocarditis. Cefalexin is not effective against infections caused by methicillin-resistant Staphylococcus aureus (MRSA), Enterococcus, or Pseudomonas. Like other antibiotics, cefalexin cannot treat viral infections, such as the flu, common cold or acute bronchitis. Cefalexin can be used in those who have mild or moderate allergies to penicillin. However, it is not recommended in those with severe penicillin allergies.
Common side effects include upset stomach and diarrhea. An allergic reaction and infection with Clostridium difficile, a type of diarrhea, is also possible. To date, no evidence of harm to the baby has been found when used during pregnancy or breast feeding. It can be used in children and those over 65 years of age. Those with kidney problems may require a decrease in dose.
In 2012, cefalexin was one of the top 100 most prescribed medications in the United States. In Canada, it was the 5th most common antibiotic used in 2013. In Australia, it is one of the top 15 most prescribed medications. Cefalexin was developed in 1967 and first marketed in 1969 and 1970 by a number of companies, including Glaxo Wellcome and Eli Lilly and Company under the names Keflex and Ceporex, among others. Generic drug versions are available under several other trade names and are inexpensive. Cefalexin is on the World Health Organization’s List of Essential Medicines, the most important medications needed in a health system.
Basic Info of cefa-iskia
Basic Info
Numbering system
Properties
Safety Info
Basic Info
Chemical Name | cephalexin |
Synonyms | Cephalexin hydrate;Cephalexin; |
CAS No. | 15686-71-2 |
Molecular Formula | C16H17N3O4S |
Molecular Weight | 347.38900 |
PSA | 138.03000 |
LogP | 1.47400 |
Numbering system
RTECS number | XI0350000 |
EINECS number | 239-773-6 |
PubChem number | 24860698 |
MDL number | MFCD00056877 |
Properties
Appearance & Physical State | white crystalline powder |
Density | 1.5g/cm3 |
Boiling Point | 727.4ºC at760mmHg |
Melting Point | 196-198ºC |
Flash Point | 393.7ºC |
Storage Condition | 2-8ºC |
Vapor Pressure | 3.27E-22mmHg at 25°C |
Safety Info
RTECS | XI0350000 |
Safety Statements | S22-S36/37-S45 |
HS Code | 3003201900 |
WGK Germany | 3 |
Risk Statements | R42/43 |
Hazard Codes | Xn |
Caution Statement | P261; P280; P342 + P311 |
Hazard Declaration | H317; H334 |
Symbol | GHS08 |
Signal Word | Danger |
What is Cephalexin?
- With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives. One such product is Cephalexin which has developed particularly rapidly in recent years. Do you know about Cephalexin ?
- The official answer:Cefadroxil is the first-generation cephalosporin, also known as “Pioneer IV”, belongs to the β-lactam class. It can inhibit the synthesis of the cell wall and make the cell contents swell to the point of rupture and dissolution, killing bacteria. It is effective against a variety of Gram-positive and Gram-negative bacteria (such as Staphylococcus, Pasteurella, and Escherichia coli). Pseudomonas spp. and Aspergillus spp. are usually resistant. Maintenance of blood levels above the MIC is critical to drug action, and prolonged dosing intervals or missed doses can reduce therapeutic efficacy. The dose and dosing interval is determined according to the site of infection, severity, and pathogenic bacteria. In severe or acute infections, the dose may be doubled or the dosing frequency increased. This product is toxic to rabbits and should be used only for specific indications.
What’s the application of Cephalexin?
Cefadroxil is the first-generation cephalosporin. Cefadroxil is mainly used for respiratory tract infections, urinary tract infections, obstetric and gynecological infections, skin and soft tissue infections and gonorrhea caused by sensitive bacteria, etc. It is the first synthetic oral cephalosporin that is stable to acid and penicillinase. Its antibacterial mechanism, antibacterial spectrum, and indications are similar to cefothiophene, but its antibacterial strength is weaker than the latter and cefothiophene, and it is used for lighter infections.
Conclusion
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