matrine,1-oxide, Promotion Season Now in Store and Free Sample for Testing with Factory Price
- Chemical Name: Ammothamnine
- CAS No.: 16837-52-8
- Molecular Fomula: ：C15H24N2O2
- Molecular weight：264.36
- Appearance: white powder
- Sample：Available
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Description of matrine,1-oxide
- Oxymatrine (matrine oxide, matrine N-oxide, matrine 1-oxide) is one of many quinolizidine alkaloid compounds extracted from the root of Sophora flavescens, a Chinese herb. It is very similar in structure to matrine, which has one less oxygen atom. Oxymatrine has a variety of effects in vitro and in animal models, including protection against apoptosis, tumor and fibrotic tissue development, and inflammation. Furthermore, oxymatrine has been shown to decrease cardiac ischemia (decreased blood perfusion), myocardial injury, arrhythmias (irregular heartbeats), and improve heart failure by increasing cardiac function.
Basic Info of matrine,1-oxide
Basic Info
Numbering system
Properties
Basic Info
| Chemical Name | oxymatrine |
| Synonyms | (7aS,13aR,13bR,13cS)-dodecahydro-1H,5H,10H-dipyrido[2,1-f:3’,2’,1’-ij][1,6]naphthyridin-10-one 4-oxide;(4R,7aS,13aR,13bR,13cS)-dodecahydro-1H,5H,10H-dipyrido[2,1-f:3’,2’,1’-ij][1,6]naphthyridin-10-one 4-oxide;Ammothamnine;Oxymatrine; |
| CAS No. | 16837-52-8 |
| Molecular Formula | C15H24N2O2 |
| Molecular Weight | 264.36300 |
| PSA | 49.74000 |
| LogP | 1.78100 |
Numbering system
| EINECS number | 605-514-4 |
Properties
| Refractive Index | 1.637 |
| Vapor Pressure | 0mmHg at 25°C |
What is Ammothamnine?
- With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives. One such product is Ammothamnine which has developed particularly rapidly in recent years. Do you know about Ammothamnine?
- The official answer：Bittersweet, with molecular formula C15H24N2O, is made from the dried roots, plants, and fruits of the legume Sophora flavescens Ait, extracted by organic solvents such as ethanol, etc. Bittersweet is an alkaloid, generally known as the total alkaloids of bittersweet, whose main components are bittersweet, lacustrine, lacustrine oxide, and lacustrine. The main components of the alkaloids are bitter ginseng, lacustrine, lacustrine oxide, lacustrine, and other alkaloids, with the highest content of bitter ginseng and lacustrine oxide. Other sources are Sophora substrata (Shandong) and Sophora alopecuroides, an alkaloid in the above-ground part.
What’s the application of Ammothamnine?
- Picrasin is used in medicine, pesticide, veterinary medicine, etc. Bittergins have anti-tumor, anti-bacterial, anti-parasitic, anti-inflammatory, anti-swelling, and diuretic effects and reduce leukopenia caused by cyclophosphamide. In the anti-tumor, oxidized bitter ginseng base has the effect of lowering glutamic-alanine transaminase. In combination with thymidine for CHB, it has the effect of regulating the immune status of the body and improving liver function, and has a significant effect on the recovery of liver function, raising albumin, lowering globulin, and raising leukocytes. It has a protective effect on liver failure and has no obvious adverse effects and toxic side effects on the kidney. It is used for content determination/identification/pharmacological experiments, etc. Pharmacological efficacy: It has diuretic, anti-pathogenic and immunological effects. Some studies found that oxidized bitter ginseng alkaloids have inhibitory effects on lung cancer and gastric cancer cell-induced vascular endothelial cell proliferation isolated from bitter ginseng. Anti-fibrotic. Nerve protection. A traditional Chinese medicine, used in the treatment of the anti-hepatitis B virus.
Conclusion
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