3-Hydroxy-gamma-butyrolactone, Promotion Season Now in Store and Free Sample for Testing with Factory Price
- Chemical Name: (S)-3-Hydroxy-gamma-butyrolactone
- CAS No.: 7331-52-4
- Molecular Fomula: ： C4H6O3
- Molecular weight： 102.09
- Appearance: Colorless liquid
- Sample：Available
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Basic Info of 3-Hydroxy-gamma-butyrolactone
Basic Info
Numbering system
Properties
Safety Info
Basic Info
| Chemical Name | (S)-4-Hydroxydihydrofuran-2(3H)-one |
| Synonyms | (4S)-4-hydroxyoxolan-2-one; |
| CAS No. | 7331-52-4 |
| Molecular Formula | C4H6O3 |
| Molecular Weight | 102.08900 |
| PSA | 46.53000 |
| LogP | -0.70580 |
Numbering system
| MDL number | MFCD00211247 |
Properties
| Appearance & Physical State | clear to pale yellow liquid |
| Density | 1.24 |
| Boiling Point | 98 -100ºC at 0.1mmHg |
| Melting Point | 1.24ºC |
| Flash Point | >110ºC |
| Refractive Index | 1.463-1.466 |
| Storage Condition | 2-8ºC |
Safety Info
| Safety Statements | S26-S37/39 |
| Risk Statements | R36/37/38 |
| Hazard Codes | Xi |
What is 3-Hydroxy-gamma-butyrolactone?
With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives. One such product is (S)-3-Hydroxy-gamma-butyrolactone which has developed particularly rapidly in recent years. Do you know about (S)-3-Hydroxy-gamma-butyrolactone ?
The official answer：(S)-3-hydroxy-gamma-butyrolactone is a chemical compound with the chemical formula C4H6O3. boiling point98-100°C0.3mmHg(lit.)density1.241g/mLat25°C(lit.)refractive indexn20/D1.464(lit.)flashpoint>230°F storage conditionsInertatmosphere, 2-8°CAcidity coefficient(pKa)12.87±0.20(Predicted)Opticalactivity[α]21/D81°,c=2inethanolWater solubilityMisciblewithwater,alcoholandotherorganicsolvent. Immisciblewithlightpetroleum.
What’s the application of 3-Hydroxy-gamma-butyrolactone?
Used as an organic synthesis intermediate use Avastatin calcium intermediate use it is a very important organic synthesis intermediate, but also a very important chiral source (ChiralPool). It is mainly used as a key intermediate of the regulator (R)-γ-hydroxy-β-Q hydroxybutyric acid [(R)-GABOB], (R)-GABOB is used to treat hyperlipidemia; (s)-Oxiracetam is a promoter of brain metabolism, also out of its synthesis; its reduction can yield (s)-3-hydroxytetrahydrofuran, the latter is an important intermediate in the treatment of AIDS drugs; from it, The (s)-3-hydroxy-4-bromobutyric acid synthesized from it is a potential tranquilizer; its conversion to (s)-5-hydroxymethyl-1,3-azole-2-one yields the latest – generation of antibacterial drugs; in addition, (s)-N-methyl-3-hydroxypyrrole and (R)-
Conclusion
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