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• Chemical Name:  Calcium dobesilate
• CAS No.:     20123-80-2
• Molecular Fomula: ： 2C6H5O5S
• Molecular weight：418.41
• Appearance: white poewder
• Sample：Available

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Basic Info
Numbering system
Properties
Safety Info
Basic Info

Numbering system

Properties

Safety Info

What is Calcium dobesilate?

• With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives. One such product is Calcium dobesilate   which has developed particularly rapidly in recent years. Do you know about Calcium dobesilate  ?
• The official answer：Calcium Dobesilate acts on the endothelial cell layer and basal layer of capillary blood vessels, regulates and improves capillary permeability and flexibility, increases the resistance of capillary walls, reduces their permeability, has an activating effect on the lymphatic circulation system, reduces blood and plasma viscosity, corrects the albumin/globulin ratio, reduces platelet hyper aggregation, and reduces plasma viscosity, thus preventing thrombosis. In addition, it can also inhibit the production of sorbitol (the mechanism of action in the treatment of diabetic retinopathy) and promote the formation of collagen fibers, the main component of the arterial wall.

What’s the application of Calcium dobesilate?

• Calcium hydroxybenzenesulfonate inhibits the hyperpermeability of microvessels caused by vasoactive substances (histamine, 5-hydroxytryptamine, bradykinin, hyaluronidase, prostaglandin), reduces intimal damage, improves collagen biosynthesis in the basement membrane, improves capillary wall permeability, increases the flexibility of red blood cells, reduces blood viscosity, improves lymphatic reflux, and thus reduces pathological hyperpermeability of microvascular walls. 2. Calcium hydroxybenzenesulfonate can reduce the level of fibrinogen and globulin, reduce the hyper aggregation of red blood cells, activate fibrinase activity, increase the lysis capacity of blood fibrin, thus reducing the viscosity of blood. Reduce the synthesis and release of platelet aggregation factors, inhibit a variety of aggregation factors, cause aggregation reaction and platelet spontaneous aggregation, reduce platelet activity, prevent thrombosis, its effect is dose-related. 3. For microvascular lesions, calcium hydroxybenzenesulfonate can increase the caliber of fine arteries and fine veins, increase the number of capillary openings, significantly accelerate blood flow, and significantly improve the effect of microcirculation. Eliminate or relieve edema, capillary oozing, heaviness, and pressure feeling of lower limbs.4. Calcium hydroxybenzenesulfonate significantly reduce the content of sorbitol, blocks the channel of sugar to sorbitol, and inhibits the dysfunction caused by increased sorbitol in blood cells.

Conclusion

Sincere to the customer and in good faith of quality is our forever followed motto. It’s the basement to be a human and do business. We take all responsibility for our products and service sincerely. We are a company integrating R&D, production, and sales. The design, research, and development of pharmaceutical intermediates including more than 330 kinds of pharmaceutical intermediates such as Anti-infectives, Cardiovascular and Cerebrovascular Systems, Digestive System, Santi-tumor, Nervous System, Geriatric Drugs, and Gynecological Drugs. At the same time, we have more than 4,000 factories in strategic cooperation with nearly 50,000 chemical products, so we can provide you with a one-stop purchasing service, which greatly saves customers’ procurement costs and time.

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