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Pantoprazole, sold under the brand name Protonix among others, is used for short-term treatment of erosive esophagitis associated with gastroesophageal reflux disease (GERD), maintenance of healing of erosive esophagitis, and pathological hypersecretory conditions including Zollinger-Ellison Syndrome.
Some common side effects of pantoprazole use in adults include: headache, diarrhea, nausea, abdominal pain, vomiting, flatulence, dizziness, and joint pain (>2%). Use of pantoprazole for a long period of time may lead to chronic inflammation of stomach lining or atrophic gastritis, vitamin B-12 deficiency, and low magnesium.
Pantoprazole is a proton pump inhibitor drug that inhibits gastric acid secretion. It works on gastric parietal cells to irreversibly inhibit (H+/K+)-ATPase function and suppress the production of gastric acid.
Basic Info
Numbering system
Properties
Safety Info
Basic Info
| Chemical Name | pantoprazole |
| CAS No. | 102625-70-7 |
| Molecular Formula | C16H15F2N3O4S |
| Molecular Weight | 383.37000 |
| PSA | 105.54000 |
| LogP | 3.75000 |
Numbering system
| UNII | D8TST4O562 |
Properties
| Appearance & Physical State | almost white solid |
| Density | 1.51 g/cm3 |
| Boiling Point | 586.9ºC at 760 mmHg |
| Melting Point | 139-140ºC, decomposes |
| Flash Point | 308.7ºC |
| Refractive Index | 1.642 |
| Vapor Pressure | 9.37E-14mmHg at 25°C |
Safety Info
| Safety Statements | S22-S26-S36/37/39-S45 |
| WGK Germany | 3 |
| Risk Statements | R20/21/22 |
| Hazard Codes | Xn |
Anti-ulcer drugs. Proton pump inhibitor of the stomach. For the treatment of active peptic ulcers, reflux esophagitis, and Cho-Israeli syndrome. For the treatment of active peptic ulcer reflux esophagitis and Cho-Israeli syndrome.
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