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• Chemical Name:  Vorinostat
• CAS No.:     149647-78-9
• Molecular Fomula: ：C14H20N2O3
• Molecular weight：264.32
• Appearance: white powder
• Sample：Available

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Description of Zolinza

• Vorinostat (rINN) also known as suberanilohydroxamic acid (suberoyl+anilide+hydroxamic acid abbreviated as SAHA) is a member of a larger class of compounds that inhibit histone deacetylases (HDAC). Histone deacetylase inhibitors (HDI) have a broad spectrum of epigenetic activities.
  Vorinostat is marketed under the name Zolinza for the treatment of cutaneous T cell lymphoma (CTCL) when the disease persists, gets worse, or comes back during or after treatment with other medicines. The compound was developed by Columbia University chemist Ronald Breslow and Memorial Sloan-Kettering researcher Paul Marks.

Basic Info of Zolinza

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Properties

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What is Vorinostat?

• With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives. One such product is Vorinostat   which has developed particularly rapidly in recent years. Do you know about Vorinostat?
• The official answer：Vorinostat is a group of protein deacetylase (HDAC) inhibitors. It can act by inducing cell differentiation, blocking the cell cycle, and inducing cellular regulation. Treatment of cutaneous T-cell lymphoma (CTCL, a type of non-Hodgkin’s lymphoma) that exacerbates, persists, and relapses, or fails after treatment with two systemic agents.CTCL is a leukocyte-type T-cell carcinoma that affects the skin.

What’s the application of Vorinostat?

Vorinostat is a novel molecularly targeted antitumor drug that causes cell cycle arrest and/or apoptosis by inhibiting histone deacetylase (HDAC). It is the first HDAC inhibitor approved by the FDA for the treatment of cutaneous T-cell lymphoma (CTCL) with significant skin invasion that has progressed, become resistant, or relapsed after two systemic regimens.

Conclusion

Sincere to the customer and in good faith of quality is our forever followed motto. It’s the basement to be a human and do business. We take all responsibility for our products and service sincerely. We are a company integrating R&D, production, and sales. The design, research, and development of pharmaceutical intermediates including more than 330 kinds of pharmaceutical intermediates such as Anti-infectives, Cardiovascular and Cerebrovascular Systems, Digestive System, Santi-tumor, Nervous System, Geriatric Drugs, and Gynecological Drugs. At the same time, we have more than 4,000 factories in strategic cooperation with nearly 50,000 chemical products, so we can provide you with a one-stop purchasing service, which greatly saves customers’ procurement costs and time.

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