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- Chemical Name: Zuclopenthixol
- CAS No.: 53772-83-1
- Molecular Fomula: C22H25ClN2OS
- Molecular weight:400.96
- Appearance: White powder
- Sample:Available
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Description of Unii-47isu063sg
Zuclopenthixol (Cisordinol, Clopixol, Acuphase), also known as zuclopentixol, is a typical antipsychotic drug of the thioxanthene class. It was introduced in 1976 by Lundbeck. It is the cis-isomer of clopenthixol.
Zuclopenthixol is not approved for use in the United States.
Basic Info of Unii-47isu063sg
Basic Info
Numbering system
Properties
Basic Info
Chemical Name | zuclopenthixol |
Synonyms | Zuclopenthixol; |
CAS No. | 53772-83-1 |
Molecular Formula | C22H25ClN2OS |
Molecular Weight | 400.96500 |
PSA | 52.01000 |
LogP | 4.11210 |
Numbering system
EINECS number | 258-758-5 |
Properties
Density | 1.289g/cm3 |
Boiling Point | 577.4ºC at 760mmHg |
Melting Point | 56-60ºC |
Flash Point | 303ºC |
Refractive Index | 1.675 |
Storage Condition | -20ºC Freezer, Under Inert Atmosphere |
What is Zuclopenthixol?
- With the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives. One such product is Zuclopenthixol which has developed particularly rapidly in recent years. Do you know about Zuclopenthixol ?
- The official answer:Chuchlorothiazide is a thioxanthene derivative, the cis-isomer of chlorpheniramine, which acts by blocking dopamine receptors and has significant antipsychotic effects and specific sedative effects, especially for schizophrenic patients, with anti-methylphenidate induced stereotypy and anti-apomorphine effects, this product can inhibit conditioned avoidance reaction and rigidity, 10 times stronger than chlorpromazine. The acute toxicity and chronic toxicity of Chuchlorothiazide are low, and no toxicity is found at therapeutic doses; no toxicity needs special attention when used in women of childbearing age; there is no toxicity such as mutagenicity and carcinogenicity, but occasional extrapyramidal reactions, motor difficulties, inability to sit still, gastrointestinal function and cardiac conduction disorders, salivary and sweat secretion disorders, cholestasis, seizures, corneal or crystal clouding, amenorrhea, breast milk overflow, etc., and the use of the drug Tiredness is easy at the beginning of the drug. It is suitable for the treatment of psychosis with symptoms of anxiety and hallucinations, delusional-hallucinatory schizophrenia, adolescent dementia, mania, and anxiety cycle psychosis; restlessness, excitement, mental confusion caused by psychiatric factors, brain atrophy process, post-traumatic psychosis, tremor prodrome, etc., especially for elderly patients. It has been marketed in more than 30 countries in Europe, Latin America, Canada, Mexico, etc.
What’s the application of Zuclopenthixol?
- Can increase the effects of alcohol, barbiturates, and other CNS depressants. 2. Can enhance the effects of antihypertensive drugs. 3. Can diminish the effects of levodopa and adrenaline drugs. 4. Combined with metoclopramide and piperazine can increase the occurrence of extrapyramidal symptoms. 5. Combined with lithium salts can cause brain damage, extrapyramidal reactions, and movement disorders. 6.Can affect the effects of insulin and glucose. The dose should be adjusted in diabetic patients. For acute and chronic schizophrenia and other psychiatric disorders, especially with hallucinations, delusions, thought disorders, and symptoms of agitation, restlessness, hostility, and aggression.
Conclusion
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